How to Beat Plague Inc. Nano-Virus on Normal

Updated on March 11, 2015

Plague Inc.'s Nano-Virus

Plague Inc.'s Nano-Virus is a pesky little bugger. It took me two weeks to build this tutorial and I have finally done it. It is a hard level, so if you don't get it the first time, don't worry. I do apologize. I have done it twice now and used a few genetic codes this time to make it a little easier and faster. This method will work if you do the same. Good luck!

Start your Nano-Virus with the following genes:

  • Metabolic Hijack (Optional)
  • Genetic Mimic
  • Aquacyte
  • Extremophile
  • Ionised Helix

Note: This plague is kind of tough. Keep in mind firstly that you'll need to allow your symptoms except insomnia.

  1. Start your plague in Brazil.
  2. Build your DNA points to 5. Abilities: Code Fragment Interception.
  3. Build your DNA points to 10. Transmissions: Water 1; Symptoms: Cysts.
  4. Build your DNA points to 10. Abilities: Code Segment Interception; Symptoms: Abscesses.
  5. Build your DNA points to 10. Transmissions: Insect 1.
  6. Build your DNA points to 10. Abilities: Radical Elements Stabilised.
  7. Build your DNA points to 10. Abilities: Cold Resistance 1.
  8. Build your DNA points to 15. Abilities: Drug Resistance 1.
  9. Build your DNA points to 15. Transmissions: Bird 1.
  10. Build your DNA points to 25. Abilities: Encryption Breached, Genetic Hardening 1.
  11. Build your DNA points to 20. Abilities: Genetic Reshuffle 1; Symptoms: Sneezing.
  12. Build your DNA points to 30. Abilities: Cold Resistance 2.
  13. Build your DNA points to 18-20. Transmissions: Water 2.
  14. Build your DNA points to 20. Abilities: Genetic Reshuffle 2.
  15. Build your DNA points to 35. Transmissions: Insect 2; Symptoms: Fever.
  16. Build your DNA points to 60. Abilities: Genetic Reshuffle 3, Genetic Hardening 2; Symptoms: Skin Lesions.
  17. Devolve any uber deadly symptoms that may evolve until everyone is infected.
  18. Build your DNA points to 100. Symptoms: Insomnia, Paranoia, Inflammation, Paralysis.
  19. Wait until everyone is infected or very close, then use the deadliest symptoms to start murdering your people.

Be sure to like and comment. I want to know how fast you killed everyone!

Video: Plague Inc. Evolved Nano-Virus Normal Walkthrough

About the Author

Hey guys, I'm ChillBilly aka Ashleign. I have been playing video games for more than 20 years. I enjoy a good bit of strategy style games mixed with online economies. MMOs are my specialty, but I do enjoy all kinds of games. My experience with Plague Inc. started when I picked up the game on my mobile phone. I immediately was hooked due to a long interest I have had in biology. I posted my first tutorial here on HubPages and it was so popular that I decided to make more.

I love helping people, and when I receive good comments and compliments, I feel that I have accomplished something. Please let me know what you thought of this tutorial in the comments below!

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    • profile image

      Anonymous 3 days ago

      654 days

      61% Cure


    • profile image

      Kenz 13 days ago

      505 days

      50% cure


    • profile image

      Felecia 2 weeks ago

      560 Days

      57% Cure


    • profile image

      Chris boyst 2 weeks ago

      493 days



    • profile image

      Mink 5 weeks ago

      581 days

      50% cured


    • profile image

      Hipkkier162 5 weeks ago

      Killed everyone but Greenland

    • profile image

      Nate 5 weeks ago

      576 days

      No genes

      56% cure

      Game crashed before I could see the score...

    • profile image

      Brayden 6 weeks ago




    • profile image

      Devin 6 weeks ago

      546 days...53% cure progress... 17370 score

    • profile image

      Aria 7 weeks ago

      651 days

      Cure Progress: 53%

      Used no genes.

      Strayed off the toutorial at devolve any uber deadly symptoms.

    • profile image

      Darren 4774 8 weeks ago

      574 days, no genes, 61% cure

    • profile image

      Assemblers 2 months ago

      Killed everyone in 620 days!!! Thank you!!!

    • profile image

      EpicGrimm 2 months ago

      Been using your tuts to get thru everything on normal, as I always get symptom happy too early. Lol :) but here ya go:

      Time: 601 Days

      Cure Progress: 49%

      Score: 14010

    • profile image

      Tompie 2 months ago

      I love this website it has helped me with a lot more than just the nano virus!!

    • profile image

      Darrin 2 months ago

      628 days 50% thanks

    • profile image

      Dustin 2 months ago

      I won in 592 days

    • profile image

      uchboy 2 months ago

      601 days cure 57% score 13460

    • profile image

      Neryma921 2 months ago

      627 days! Cure @ 53% score 9730!!

    • profile image

      Ladislaus 2 months ago

      578 days and 90%

    • profile image

      Kimmy 2 months ago

      578 days, cure 52%

      I forgot the score.

      I didn't use any genes either.

    • profile image

      Xavier Ramirez 3 months ago

      Its easy, the special genes aren't that important, but they're useful.and I succeeded first try, along with the prion and fungus!!!

    • profile image

      Aldones 3 months ago

      If you need the correct genes, just do a few casual runs to accumulate most of them. I was able to use this guide without all the required genes, using the best ones I had.

    • profile image

      TKT 3 months ago

      Your other tutorials were exstreamly helpful, however I cannot do this one because I don't have the right genes. Please can you update this tutorial so you don't have to use genes

    • profile image

      Transpoin 3 months ago

      479 days, cure 44%, 20790 final score

    • profile image

      Hope 3 months ago

      594 days, 57% cure, 12910 final score. Thanks fam I've been stuck on this for a few weeks.

    • profile image

      Alix 3 months ago

      Only took 671 days to wipe out humanity

    • profile image

      Geoff KCMO 3 months ago

      700 days...58% cure 9670 pts. Allowed some extra points to accrue, but nice tutorial...speed up ftime for eradication by throwing all symptoms into the mix.

    • profile image

      Henta 3 months ago

      740 Days with 68% cure

    • profile image

      Jacob 3 months ago

      Days: 599

      Cure: 59%

      DNA Sequence: Complex

      Score Total: 11950

    • profile image

      Liljja Winther 3 months ago

      Thank you so much! Killed everyone in 548 days on my try. They fought bravely but only got the cure up to 52%.

    • profile image

      Grady 3 months ago

      I wiped out the earth with the nano virus in 618 days

    • profile image

      david 3 months ago

      Started in India, 450 days, Cure 34% , Points 16320

    • profile image

      Kelly 4 months ago

      546 Days / Cure 55% / 14060 points

      I was having so much trouble with the nano virus on my own. Thank you so much for the guide! You're an evil genius :)

    • profile image

      smhailey 4 months ago

      I used your guide to beat the Nano-Virus. It took me 578 days (57% cure & 13,300 points). I only have 6 genes unlocked (thanks to your guides) so I used the following: ATP Boost, Travel Genes, Ionised Helix, Darwinist, & Xerophile. Thanks again for writing these guides. I’m learning a ton about this game.

    • profile image

      Cat lover 4 months ago

      414 days it went by fast thanks for the tips!

    • profile image

      Cat 07 5 months ago

      548 days

      51% cure

      13130 points

    • profile image

      Jeff 5 months ago




      Ashleigh awesomeness-110%

    • profile image

      Bido 5 months ago

      Started in India instead of Brazil still worked great, 737days, 60%cure, love your tutorials, thanks

    • profile image

      Anshul Agrawal 5 months ago


      Cure 58%

      Points 12470

    • profile image

      Hanbanan 5 months ago

      609 days 55% cure!

    • profile image

      Hii 5 months ago

      522 days, with none of the extra genes!

    • profile image

      Ryan 5 months ago

      Killed in 614 days, 112 DNA left, cure at 58%

    • profile image

      sara 5 months ago

      killed everyone in 682, cure 55% 107 dna

    • profile image

      AmiTo 6 months ago

      548 days with 53% cure and 3 biohazards. Thanks, Ashleign! :)

    • profile image

      Jake H 6 months ago

      Didn't have any of those gene helper things but 554 with 50%!!! thanks!

    • profile image

      Just Janet 6 months ago

      Brilliant! Worked on the first try. Finished in 606 days 55% cured.

    • profile image

      Britt Howard 6 months ago

      Wiped out humans in 570 days! 40 DNA points leftover after deadliest symptoms used. Cure only 55%!

    • profile image

      V1rus47 6 months ago

      590 days, 53% finished. Almost followed all the steps my disease keeps evolving. And thanks for the help

    • profile image

      Nekomaster 6 months ago

      got it on my first try with out the special genes. I probably just got lucky.

      Thanks for all your other tutorials, now I can move on to making a Bio-weapon :)

      ALso it might help if people put a few DNA points into symptoms that will help slow down the cure like paronioa and anemia to get the walking dead combo

    • profile image

      Ainzo 7 months ago

      561 days - 49% :) - thank you!!

    • profile image

      Chantel 7 months ago

      583 days and cure at 49% . Thank you so much for the walkthrough. Couldn't have done it without you!

    • profile image

      Pascal 7 months ago

      4 day -1000% cure

    • profile image

      James 7 months ago

      571 days 53% cure

    • profile image

      Level one 7 months ago

      622 days using guide, this was my second try.

    • profile image

      SeanK 7 months ago

      473 days, 41% cure

    • profile image

      lind 7 months ago

      635 days

    • profile image

      Seifer 8 months ago

      492 days, awesome tutorial

    • profile image

      Anonymous 8 months ago

      I did it in 534 days in Normal mode! This guide was extremely helpful

    • profile image

      Jace Bond 8 months ago

      I did it in 760 Days! Amazing! Didn’t follow exactly, but mostly! Thank you!

    • profile image

      Vitiate 8 months ago

      First go and did it in 537 days, great guide.

    • profile image

      Bexx 8 months ago

      600 Days :D

    • profile image

      Frances 8 months ago

      Five hundred twenty-seven days.

    • profile image

      Mike 8 months ago

      561 days

    • amyzzzzz123 profile image

      amyzzzzz123 8 months ago

      Beat it in 577 days :) thanks!

    • profile image

      orteam 8 months ago

      Worked :)

    • profile image

      MartianArcher 8 months ago

      First try and won. Excellent tutorial

    • profile image

      Shrim 8 months ago

      I got 684 days.

    • profile image

      Martint9179 8 months ago

      I messed up by going a bit too fast and skipping a step, so I had to devolve 2 symptoms. Even with the screw-up, I still killed off the world in 540 days with the cure at 51% on the first try. I didn't have any of the genes you listed at the top, so I used Aquacyte and Xerophile, but it still worked out really well. Thanks for uploading this strategy. Keep up the good work.

    • profile image

      autumn 8 months ago

      Started in Brazil, 587 days and cure was at 56%; but I didn't have genetic mimic, metabolic hijack, or extromophile.

    • profile image

      Cool 8 months ago

      573 days and 51 cure percent

    • profile image

      Harry 8 months ago

      Its work. 592 Days, 48% cure, I started it in China.

    • profile image

      David 9 months ago

      Worked in 685 days. I started in Greenland because others said it was hard to get it there. Otherwise I followed the directions exactly.

    • profile image

      Yeet 9 months ago

      lost, greenland never infected

    • profile image

      Amy 9 months ago

      I got the sterile ship problem right away and never spread to Greenland.

    • profile image

      Chriz 9 months ago

      797@ 67 cure was pretty interesting

    • profile image

      maor 9 months ago

      781 .. first try

      at first it was stressfull because the world started working the cure from the few first infected people & it runs very fast.

      at the end, the cure was on 60%.

      tnx ....

    • profile image

      Tayler 9 months ago

      645, thank you!!

    • profile image

      Tassy89 9 months ago

      Hi! Thanks so much for posting the technique. I killed everyone in 513 days. Great strategty.

    • profile image

      Ted4523 10 months ago

      Thank you! It worked so well! I beat it in 650 days!

    • profile image

      bobybob 10 months ago

      495 days ! Awesome

    • profile image

      Poop 10 months ago

      It worked

    • profile image

      Britt 10 months ago

      646 days

    • profile image

      Mfall 10 months ago

      I love your tutorials. I have done most of these and the ones I have done worked great. This one didn't work when I started in Brazil. I started in Saudi Arabia the second time and it worked.

    • profile image

      Emil 10 months ago

      551 days!!!

    • profile image

      Luke Hazell 10 months ago

      Aced it in 522days i think

    • profile image

      Johanna 11 months ago

      I tried a few times and was really struggling with the nano virus - but these guidelines killed everyone off with the cure only half complete. Thanks so much!

    • profile image

      Burgie 11 months ago

      Managed to do it in 590 days :)

    • profile image

      RKMiateri 11 months ago

      Named Humanity. Killed without problems...

    • profile image

      noah 11 months ago

      mine was called donald trump and it killed everyone in 396 days without genes.... i knew he would get work done quickly but not like this!

    • profile image

      crayphish 11 months ago

      Wonderful!! 661 days. Thanks again!

    • profile image

      Brandon G 12 months ago

      I beat it in just 526 days... Thanks alot

    • profile image

      Steven 12 months ago

      My Nano virus called Boo, just wiped out the world in 597 days!

    • profile image

      Mark 12 months ago

      Thanks so much for your guidelines and tutorials which have been a major help in beating each plague. In a few cases I have put my own spin on it to beat a couple of the plagues but without your help I would probably still be stuck. I do have on question if you would help me with--how do you acquire the different genes that helped you beat the nano virus? I have the full game but cant find where you get them. Do you win them or buy them? Please help with this issue. Thank you very much.

    • profile image

      Lucas 12 months ago

      Managed to do it first try in less than 400 days, without genes! you're the best

    • profile image

      le 12 months ago

      amazing. first time and worked perfectly.

    • profile image

      Anon82742 12 months ago

      538 days and 38% cure

    • profile image

      Anonymous 12 months ago

      I recomend starting in saudi Arabia because of all the air traffick to and from there

    • profile image

      may1989 12 months ago

      Start in Brazil with no DNA modification, finished in 609 days at 62%. Thanks!

    • profile image

      SASA 12 months ago

      382 DAYS

      32% CURE !


    • profile image

      Kerstian 12 months ago

      Thank you (: took 520 days at 48% cure! Woop woop