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How to Beat Plague Inc. Nano-Virus on Normal

Updated on March 11, 2015

Plague Inc.'s Nano-Virus

Plague Inc.'s Nano-Virus is a pesky little bugger. It took me two weeks to build this tutorial and I have finally done it. It is a hard level, so if you don't get it the first time, don't worry. I do apologize. I have done it twice now and used a few genetic codes this time to make it a little easier and faster. This method will work if you do the same. Good luck!

Start your Nano-Virus with the following genes:

  • Metabolic Hijack (Optional)
  • Genetic Mimic
  • Aquacyte
  • Extremophile
  • Ionised Helix

Note: This plague is kind of tough. Keep in mind firstly that you'll need to allow your symptoms except insomnia.

  1. Start your plague in Brazil.
  2. Build your DNA points to 5. Abilities: Code Fragment Interception.
  3. Build your DNA points to 10. Transmissions: Water 1; Symptoms: Cysts.
  4. Build your DNA points to 10. Abilities: Code Segment Interception; Symptoms: Abscesses.
  5. Build your DNA points to 10. Transmissions: Insect 1.
  6. Build your DNA points to 10. Abilities: Radical Elements Stabilised.
  7. Build your DNA points to 10. Abilities: Cold Resistance 1.
  8. Build your DNA points to 15. Abilities: Drug Resistance 1.
  9. Build your DNA points to 15. Transmissions: Bird 1.
  10. Build your DNA points to 25. Abilities: Encryption Breached, Genetic Hardening 1.
  11. Build your DNA points to 20. Abilities: Genetic Reshuffle 1; Symptoms: Sneezing.
  12. Build your DNA points to 30. Abilities: Cold Resistance 2.
  13. Build your DNA points to 18-20. Transmissions: Water 2.
  14. Build your DNA points to 20. Abilities: Genetic Reshuffle 2.
  15. Build your DNA points to 35. Transmissions: Insect 2; Symptoms: Fever.
  16. Build your DNA points to 60. Abilities: Genetic Reshuffle 3, Genetic Hardening 2; Symptoms: Skin Lesions.
  17. Devolve any uber deadly symptoms that may evolve until everyone is infected.
  18. Build your DNA points to 100. Symptoms: Insomnia, Paranoia, Inflammation, Paralysis.
  19. Wait until everyone is infected or very close, then use the deadliest symptoms to start murdering your people.

Be sure to like and comment. I want to know how fast you killed everyone!

Video: Plague Inc. Evolved Nano-Virus Normal Walkthrough

About the Author

Hey guys, I'm ChillBilly aka Ashleign. I have been playing video games for more than 20 years. I enjoy a good bit of strategy style games mixed with online economies. MMOs are my specialty, but I do enjoy all kinds of games. My experience with Plague Inc. started when I picked up the game on my mobile phone. I immediately was hooked due to a long interest I have had in biology. I posted my first tutorial here on HubPages and it was so popular that I decided to make more.

I love helping people, and when I receive good comments and compliments, I feel that I have accomplished something. Please let me know what you thought of this tutorial in the comments below!

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    • profile image

      Kelly 9 days ago

      546 Days / Cure 55% / 14060 points

      I was having so much trouble with the nano virus on my own. Thank you so much for the guide! You're an evil genius :)

    • profile image

      smhailey 2 weeks ago

      I used your guide to beat the Nano-Virus. It took me 578 days (57% cure & 13,300 points). I only have 6 genes unlocked (thanks to your guides) so I used the following: ATP Boost, Travel Genes, Ionised Helix, Darwinist, & Xerophile. Thanks again for writing these guides. I’m learning a ton about this game.

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      Cat lover 3 weeks ago

      414 days it went by fast thanks for the tips!

    • profile image

      Cat 07 4 weeks ago

      548 days

      51% cure

      13130 points

    • profile image

      Jeff 4 weeks ago




      Ashleigh awesomeness-110%

    • profile image

      Bido 4 weeks ago

      Started in India instead of Brazil still worked great, 737days, 60%cure, love your tutorials, thanks

    • profile image

      Anshul Agrawal 4 weeks ago


      Cure 58%

      Points 12470

    • profile image

      Hanbanan 5 weeks ago

      609 days 55% cure!

    • profile image

      Hii 6 weeks ago

      522 days, with none of the extra genes!

    • profile image

      Ryan 6 weeks ago

      Killed in 614 days, 112 DNA left, cure at 58%

    • profile image

      sara 8 weeks ago

      killed everyone in 682, cure 55% 107 dna

    • profile image

      AmiTo 2 months ago

      548 days with 53% cure and 3 biohazards. Thanks, Ashleign! :)

    • profile image

      Jake H 2 months ago

      Didn't have any of those gene helper things but 554 with 50%!!! thanks!

    • profile image

      Just Janet 2 months ago

      Brilliant! Worked on the first try. Finished in 606 days 55% cured.

    • profile image

      Britt Howard 2 months ago

      Wiped out humans in 570 days! 40 DNA points leftover after deadliest symptoms used. Cure only 55%!

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      V1rus47 2 months ago

      590 days, 53% finished. Almost followed all the steps my disease keeps evolving. And thanks for the help

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      Nekomaster 2 months ago

      got it on my first try with out the special genes. I probably just got lucky.

      Thanks for all your other tutorials, now I can move on to making a Bio-weapon :)

      ALso it might help if people put a few DNA points into symptoms that will help slow down the cure like paronioa and anemia to get the walking dead combo

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      Ainzo 3 months ago

      561 days - 49% :) - thank you!!

    • profile image

      Chantel 3 months ago

      583 days and cure at 49% . Thank you so much for the walkthrough. Couldn't have done it without you!

    • profile image

      Pascal 3 months ago

      4 day -1000% cure

    • profile image

      James 3 months ago

      571 days 53% cure

    • profile image

      Level one 3 months ago

      622 days using guide, this was my second try.

    • profile image

      SeanK 3 months ago

      473 days, 41% cure

    • profile image

      lind 3 months ago

      635 days

    • profile image

      Seifer 4 months ago

      492 days, awesome tutorial

    • profile image

      Anonymous 4 months ago

      I did it in 534 days in Normal mode! This guide was extremely helpful

    • profile image

      Jace Bond 4 months ago

      I did it in 760 Days! Amazing! Didn’t follow exactly, but mostly! Thank you!

    • profile image

      Vitiate 4 months ago

      First go and did it in 537 days, great guide.

    • profile image

      Bexx 4 months ago

      600 Days :D

    • profile image

      Frances 4 months ago

      Five hundred twenty-seven days.

    • profile image

      Mike 4 months ago

      561 days

    • amyzzzzz123 profile image

      amyzzzzz123 4 months ago

      Beat it in 577 days :) thanks!

    • profile image

      orteam 4 months ago

      Worked :)

    • profile image

      MartianArcher 4 months ago

      First try and won. Excellent tutorial

    • profile image

      Shrim 4 months ago

      I got 684 days.

    • profile image

      Martint9179 4 months ago

      I messed up by going a bit too fast and skipping a step, so I had to devolve 2 symptoms. Even with the screw-up, I still killed off the world in 540 days with the cure at 51% on the first try. I didn't have any of the genes you listed at the top, so I used Aquacyte and Xerophile, but it still worked out really well. Thanks for uploading this strategy. Keep up the good work.

    • profile image

      autumn 4 months ago

      Started in Brazil, 587 days and cure was at 56%; but I didn't have genetic mimic, metabolic hijack, or extromophile.

    • profile image

      Cool 4 months ago

      573 days and 51 cure percent

    • profile image

      Harry 4 months ago

      Its work. 592 Days, 48% cure, I started it in China.

    • profile image

      David 5 months ago

      Worked in 685 days. I started in Greenland because others said it was hard to get it there. Otherwise I followed the directions exactly.

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      Yeet 5 months ago

      lost, greenland never infected

    • profile image

      Amy 5 months ago

      I got the sterile ship problem right away and never spread to Greenland.

    • profile image

      Chriz 5 months ago

      797@ 67 cure was pretty interesting

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      maor 5 months ago

      781 .. first try

      at first it was stressfull because the world started working the cure from the few first infected people & it runs very fast.

      at the end, the cure was on 60%.

      tnx ....

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      Tayler 5 months ago

      645, thank you!!

    • profile image

      Tassy89 5 months ago

      Hi! Thanks so much for posting the technique. I killed everyone in 513 days. Great strategty.

    • profile image

      Ted4523 6 months ago

      Thank you! It worked so well! I beat it in 650 days!

    • profile image

      bobybob 6 months ago

      495 days ! Awesome

    • profile image

      Poop 6 months ago

      It worked

    • profile image

      Britt 6 months ago

      646 days

    • profile image

      Mfall 6 months ago

      I love your tutorials. I have done most of these and the ones I have done worked great. This one didn't work when I started in Brazil. I started in Saudi Arabia the second time and it worked.

    • profile image

      Emil 6 months ago

      551 days!!!

    • profile image

      Luke Hazell 6 months ago

      Aced it in 522days i think

    • profile image

      Johanna 7 months ago

      I tried a few times and was really struggling with the nano virus - but these guidelines killed everyone off with the cure only half complete. Thanks so much!

    • profile image

      Burgie 7 months ago

      Managed to do it in 590 days :)

    • profile image

      RKMiateri 7 months ago

      Named Humanity. Killed without problems...

    • profile image

      noah 7 months ago

      mine was called donald trump and it killed everyone in 396 days without genes.... i knew he would get work done quickly but not like this!

    • profile image

      crayphish 7 months ago

      Wonderful!! 661 days. Thanks again!

    • profile image

      Brandon G 8 months ago

      I beat it in just 526 days... Thanks alot

    • profile image

      Steven 8 months ago

      My Nano virus called Boo, just wiped out the world in 597 days!

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      Mark 8 months ago

      Thanks so much for your guidelines and tutorials which have been a major help in beating each plague. In a few cases I have put my own spin on it to beat a couple of the plagues but without your help I would probably still be stuck. I do have on question if you would help me with--how do you acquire the different genes that helped you beat the nano virus? I have the full game but cant find where you get them. Do you win them or buy them? Please help with this issue. Thank you very much.

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      Lucas 8 months ago

      Managed to do it first try in less than 400 days, without genes! you're the best

    • profile image

      le 8 months ago

      amazing. first time and worked perfectly.

    • profile image

      Anon82742 8 months ago

      538 days and 38% cure

    • profile image

      Anonymous 8 months ago

      I recomend starting in saudi Arabia because of all the air traffick to and from there

    • profile image

      may1989 8 months ago

      Start in Brazil with no DNA modification, finished in 609 days at 62%. Thanks!

    • profile image

      SASA 8 months ago

      382 DAYS

      32% CURE !


    • profile image

      Kerstian 8 months ago

      Thank you (: took 520 days at 48% cure! Woop woop

    • profile image

      Amber 9 months ago

      omg thank took me forever to actually figure this out and i wouldn't have been able to win it without this walkthrough :)

    • profile image

      Itx 9 months ago

      I got it on my first try, following your advice to the letter. 649 days, cure at 59 percent. Thank you!

    • profile image

      Bentheblue 9 months ago

      614 days thank you

    • profile image

      daz 9 months ago

      590 days 51% cure

    • profile image

      Lucas 9 months ago

      This works for Brutal too. Gonna try mega brutal tonight.

    • profile image

      Josie 9 months ago

      458 days 45% cure

    • Jen Anderson profile image

      Jen Anderson 9 months ago

      Awesome tutorial! 672 days 59% cure (I used the same genes as suggested as well)

      Did cure research begin nearly right away for everyone else as well? I was surprised about that, even though I beat the cure in the end...

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      densyaa 9 months ago

      557 days and 53% cure, i don't even use the genetic codes !! thank you, you are awesome !

    • profile image

      Em 9 months ago

      533 days!!

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      Neurax 9 months ago

      This tutorial is so awesome that i completed Nano-Virus not only on normal, but also on brutal.

      Greenland closed ports, but i evolved Extreme Zoonosis, and i got random non-human infection. Then i evolved one more lethal symptom, and when the cure was about to be finished, i evolved two final abilities that disable cure progress for some time. By that time there were not enough people to make cure on time.

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      DJV 10 months ago

      580 Days 47% cure with ATP Boost, Teracyte, Ionised Helix, and Hydrophile and my score was 13270 three biohazards

    • profile image

      Jay 10 months ago

      582 days with 55% cure

      I used teracyte, ionised helix and atp boost

      Also used some of the special nano virus abilities. Thanks so much for the guide!

    • profile image

      ThunderChicken 10 months ago

      Followed the guide except for starting it in Saudi Arabia. 452 days, 45% cure

    • profile image

      Tony 11 months ago

      490 days cure at 39% on my first try. Youre awesome!

    • profile image

      NeverBorn 11 months ago

      First try, 548 days, 51% cure, 18540 total score!

      I also only had Metabolic Hijack and Aquacyte genes.

    • profile image

      Chad 11 months ago

      857 days on brutal.

    • Ashleign profile image

      Ashleign 11 months ago

      No, you're amazing. Thanks for the comment!

    • profile image

      Eljay77 11 months ago

      First try! You are amazing

      566 days, 53% Cure, score 12450

    • profile image

      ThatGuyOnTheInternet 12 months ago

      591 days

      54% cure

      11220 points

      no genes


    • profile image

      Abby 12 months ago

      No Genes used

      374 Days

      60 % cure


    • profile image

      Zombies 12 months ago

      535 days 50% cure 16350 points

    • profile image

      Braydon 12 months ago

      510 days, 50% cure and most of the symptoms

    • profile image

      Luc1F3R 13 months ago

      No genes used, 641 days 60% cure

    • profile image

      Humn 13 months ago

      491 days 46%of cure dome

    • profile image

      SmugLittleF*** 13 months ago

      603 days, score is 13980.

      I did it first try.

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      Carrie 13 months ago

      NO genes used

      cure at 57%

      killed all of humanity (outside of earthquakes and flooding) in 659 days.

      10/10 would kill humanity again

    • profile image

      MandyLeigh 13 months ago

      Took me 641 days at 56 percent cure rate.

      Had to start in Greenland, because of the boarders closing. I just shaped the cold with the heat. But followed all the same steps.

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      Jen 13 months ago

      Got it on my first try...422 days, 30% cure


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      Paul Richard 13 months ago

      446 days and 30% cure

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      Justin 13 months ago

      YES!!!! I´ve completed it in 576 days with 59% cure research, and it was from my first try! Thanks!

    • profile image

      rappy 13 months ago

      551 days

      51% cure

      15800 pts

      tnx a lot!

    • profile image

      Raven 14 months ago

      Starting in Brazil didn't work for me, Greenland shut down their boarders before anyone got infected, those bastards. However, starting in Greenland and "buying" Heat Resistance I instead of Cold Resistance II worked just fine