Mobile GamesFirst Person ShootersSimulation GamesAction-Adventure GamesRPGsMMORPGsSports GamesFighting GamesStrategy GamesClassic GamesHorror GamesPuzzle GameseSportsConsoles

How to Beat Plague Inc. Nano-Virus on Normal

Updated on March 11, 2015

Plague Inc.'s Nano-Virus

Plague Inc.'s Nano-Virus is a pesky little bugger. It took me two weeks to build this tutorial and I have finally done it. It is a hard level, so if you don't get it the first time, don't worry. I do apologize. I have done it twice now and used a few genetic codes this time to make it a little easier and faster. This method will work if you do the same. Good luck!

Start your Nano-Virus with the following genes:

  • Metabolic Hijack (Optional)
  • Genetic Mimic
  • Aquacyte
  • Extremophile
  • Ionised Helix

Note: This plague is kind of tough. Keep in mind firstly that you'll need to allow your symptoms except insomnia.

  1. Start your plague in Brazil.
  2. Build your DNA points to 5. Abilities: Code Fragment Interception.
  3. Build your DNA points to 10. Transmissions: Water 1; Symptoms: Cysts.
  4. Build your DNA points to 10. Abilities: Code Segment Interception; Symptoms: Abscesses.
  5. Build your DNA points to 10. Transmissions: Insect 1.
  6. Build your DNA points to 10. Abilities: Radical Elements Stabilised.
  7. Build your DNA points to 10. Abilities: Cold Resistance 1.
  8. Build your DNA points to 15. Abilities: Drug Resistance 1.
  9. Build your DNA points to 15. Transmissions: Bird 1.
  10. Build your DNA points to 25. Abilities: Encryption Breached, Genetic Hardening 1.
  11. Build your DNA points to 20. Abilities: Genetic Reshuffle 1; Symptoms: Sneezing.
  12. Build your DNA points to 30. Abilities: Cold Resistance 2.
  13. Build your DNA points to 18-20. Transmissions: Water 2.
  14. Build your DNA points to 20. Abilities: Genetic Reshuffle 2.
  15. Build your DNA points to 35. Transmissions: Insect 2; Symptoms: Fever.
  16. Build your DNA points to 60. Abilities: Genetic Reshuffle 3, Genetic Hardening 2; Symptoms: Skin Lesions.
  17. Devolve any uber deadly symptoms that may evolve until everyone is infected.
  18. Build your DNA points to 100. Symptoms: Insomnia, Paranoia, Inflammation, Paralysis.
  19. Wait until everyone is infected or very close, then use the deadliest symptoms to start murdering your people.

Be sure to like and comment. I want to know how fast you killed everyone!

Video: Plague Inc. Evolved Nano-Virus Normal Walkthrough

About the Author

Hey guys, I'm ChillBilly aka Ashleign. I have been playing video games for more than 20 years. I enjoy a good bit of strategy style games mixed with online economies. MMOs are my specialty, but I do enjoy all kinds of games. My experience with Plague Inc. started when I picked up the game on my mobile phone. I immediately was hooked due to a long interest I have had in biology. I posted my first tutorial here on HubPages and it was so popular that I decided to make more.

I love helping people, and when I receive good comments and compliments, I feel that I have accomplished something. Please let me know what you thought of this tutorial in the comments below!

Increase our quality of service

Did this tutorial work for you?

See results


    0 of 8192 characters used
    Post Comment

    • profile image

      AmiTo 6 days ago

      548 days with 53% cure and 3 biohazards. Thanks, Ashleign! :)

    • profile image

      Jake H 7 days ago

      Didn't have any of those gene helper things but 554 with 50%!!! thanks!

    • profile image

      Just Janet 10 days ago

      Brilliant! Worked on the first try. Finished in 606 days 55% cured.

    • profile image

      Britt Howard 10 days ago

      Wiped out humans in 570 days! 40 DNA points leftover after deadliest symptoms used. Cure only 55%!

    • profile image

      V1rus47 2 weeks ago

      590 days, 53% finished. Almost followed all the steps my disease keeps evolving. And thanks for the help

    • profile image

      Nekomaster 3 weeks ago

      got it on my first try with out the special genes. I probably just got lucky.

      Thanks for all your other tutorials, now I can move on to making a Bio-weapon :)

      ALso it might help if people put a few DNA points into symptoms that will help slow down the cure like paronioa and anemia to get the walking dead combo

    • profile image

      Ainzo 3 weeks ago

      561 days - 49% :) - thank you!!

    • profile image

      Chantel 5 weeks ago

      583 days and cure at 49% . Thank you so much for the walkthrough. Couldn't have done it without you!

    • profile image

      Pascal 5 weeks ago

      4 day -1000% cure

    • profile image

      James 7 weeks ago

      571 days 53% cure

    • profile image

      Level one 7 weeks ago

      622 days using guide, this was my second try.

    • profile image

      SeanK 7 weeks ago

      473 days, 41% cure

    • profile image

      lind 7 weeks ago

      635 days

    • profile image

      Seifer 7 weeks ago

      492 days, awesome tutorial

    • profile image

      Anonymous 8 weeks ago

      I did it in 534 days in Normal mode! This guide was extremely helpful

    • profile image

      Jace Bond 8 weeks ago

      I did it in 760 Days! Amazing! Didn’t follow exactly, but mostly! Thank you!

    • profile image

      Vitiate 8 weeks ago

      First go and did it in 537 days, great guide.

    • profile image

      Bexx 8 weeks ago

      600 Days :D

    • profile image

      Frances 8 weeks ago

      Five hundred twenty-seven days.

    • profile image

      Mike 2 months ago

      561 days

    • amyzzzzz123 profile image

      amyzzzzz123 2 months ago

      Beat it in 577 days :) thanks!

    • profile image

      orteam 2 months ago

      Worked :)

    • profile image

      MartianArcher 2 months ago

      First try and won. Excellent tutorial

    • profile image

      Shrim 2 months ago

      I got 684 days.

    • profile image

      Martint9179 2 months ago

      I messed up by going a bit too fast and skipping a step, so I had to devolve 2 symptoms. Even with the screw-up, I still killed off the world in 540 days with the cure at 51% on the first try. I didn't have any of the genes you listed at the top, so I used Aquacyte and Xerophile, but it still worked out really well. Thanks for uploading this strategy. Keep up the good work.

    • profile image

      autumn 2 months ago

      Started in Brazil, 587 days and cure was at 56%; but I didn't have genetic mimic, metabolic hijack, or extromophile.

    • profile image

      Cool 2 months ago

      573 days and 51 cure percent

    • profile image

      Harry 2 months ago

      Its work. 592 Days, 48% cure, I started it in China.

    • profile image

      David 2 months ago

      Worked in 685 days. I started in Greenland because others said it was hard to get it there. Otherwise I followed the directions exactly.

    • profile image

      Yeet 2 months ago

      lost, greenland never infected

    • profile image

      Amy 3 months ago

      I got the sterile ship problem right away and never spread to Greenland.

    • profile image

      Chriz 3 months ago

      797@ 67 cure was pretty interesting

    • profile image

      maor 3 months ago

      781 .. first try

      at first it was stressfull because the world started working the cure from the few first infected people & it runs very fast.

      at the end, the cure was on 60%.

      tnx ....

    • profile image

      Tayler 3 months ago

      645, thank you!!

    • profile image

      Tassy89 3 months ago

      Hi! Thanks so much for posting the technique. I killed everyone in 513 days. Great strategty.

    • profile image

      Ted4523 3 months ago

      Thank you! It worked so well! I beat it in 650 days!

    • profile image

      bobybob 4 months ago

      495 days ! Awesome

    • profile image

      Poop 4 months ago

      It worked

    • profile image

      Britt 4 months ago

      646 days

    • profile image

      Mfall 4 months ago

      I love your tutorials. I have done most of these and the ones I have done worked great. This one didn't work when I started in Brazil. I started in Saudi Arabia the second time and it worked.

    • profile image

      Emil 4 months ago

      551 days!!!

    • profile image

      Luke Hazell 4 months ago

      Aced it in 522days i think

    • profile image

      Johanna 5 months ago

      I tried a few times and was really struggling with the nano virus - but these guidelines killed everyone off with the cure only half complete. Thanks so much!

    • profile image

      Burgie 5 months ago

      Managed to do it in 590 days :)

    • profile image

      RKMiateri 5 months ago

      Named Humanity. Killed without problems...

    • profile image

      noah 5 months ago

      mine was called donald trump and it killed everyone in 396 days without genes.... i knew he would get work done quickly but not like this!

    • profile image

      crayphish 5 months ago

      Wonderful!! 661 days. Thanks again!

    • profile image

      Brandon G 5 months ago

      I beat it in just 526 days... Thanks alot

    • profile image

      Steven 6 months ago

      My Nano virus called Boo, just wiped out the world in 597 days!

    • profile image

      Mark 6 months ago

      Thanks so much for your guidelines and tutorials which have been a major help in beating each plague. In a few cases I have put my own spin on it to beat a couple of the plagues but without your help I would probably still be stuck. I do have on question if you would help me with--how do you acquire the different genes that helped you beat the nano virus? I have the full game but cant find where you get them. Do you win them or buy them? Please help with this issue. Thank you very much.

    • profile image

      Lucas 6 months ago

      Managed to do it first try in less than 400 days, without genes! you're the best

    • profile image

      le 6 months ago

      amazing. first time and worked perfectly.

    • profile image

      Anon82742 6 months ago

      538 days and 38% cure

    • profile image

      Anonymous 6 months ago

      I recomend starting in saudi Arabia because of all the air traffick to and from there

    • profile image

      may1989 6 months ago

      Start in Brazil with no DNA modification, finished in 609 days at 62%. Thanks!

    • profile image

      SASA 6 months ago

      382 DAYS

      32% CURE !


    • profile image

      Kerstian 6 months ago

      Thank you (: took 520 days at 48% cure! Woop woop

    • profile image

      Amber 6 months ago

      omg thank took me forever to actually figure this out and i wouldn't have been able to win it without this walkthrough :)

    • profile image

      Itx 7 months ago

      I got it on my first try, following your advice to the letter. 649 days, cure at 59 percent. Thank you!

    • profile image

      Bentheblue 7 months ago

      614 days thank you

    • profile image

      daz 7 months ago

      590 days 51% cure

    • profile image

      Lucas 7 months ago

      This works for Brutal too. Gonna try mega brutal tonight.

    • profile image

      Josie 7 months ago

      458 days 45% cure

    • Jen Anderson profile image

      Jen Anderson 7 months ago

      Awesome tutorial! 672 days 59% cure (I used the same genes as suggested as well)

      Did cure research begin nearly right away for everyone else as well? I was surprised about that, even though I beat the cure in the end...

    • profile image

      densyaa 7 months ago

      557 days and 53% cure, i don't even use the genetic codes !! thank you, you are awesome !

    • profile image

      Em 7 months ago

      533 days!!

    • profile image

      Neurax 7 months ago

      This tutorial is so awesome that i completed Nano-Virus not only on normal, but also on brutal.

      Greenland closed ports, but i evolved Extreme Zoonosis, and i got random non-human infection. Then i evolved one more lethal symptom, and when the cure was about to be finished, i evolved two final abilities that disable cure progress for some time. By that time there were not enough people to make cure on time.

    • profile image

      DJV 7 months ago

      580 Days 47% cure with ATP Boost, Teracyte, Ionised Helix, and Hydrophile and my score was 13270 three biohazards

    • profile image

      Jay 8 months ago

      582 days with 55% cure

      I used teracyte, ionised helix and atp boost

      Also used some of the special nano virus abilities. Thanks so much for the guide!

    • profile image

      ThunderChicken 8 months ago

      Followed the guide except for starting it in Saudi Arabia. 452 days, 45% cure

    • profile image

      Tony 9 months ago

      490 days cure at 39% on my first try. Youre awesome!

    • profile image

      NeverBorn 9 months ago

      First try, 548 days, 51% cure, 18540 total score!

      I also only had Metabolic Hijack and Aquacyte genes.

    • profile image

      Chad 9 months ago

      857 days on brutal.

    • Ashleign profile image

      Ashleign 9 months ago

      No, you're amazing. Thanks for the comment!

    • profile image

      Eljay77 9 months ago

      First try! You are amazing

      566 days, 53% Cure, score 12450

    • profile image

      ThatGuyOnTheInternet 10 months ago

      591 days

      54% cure

      11220 points

      no genes


    • profile image

      Abby 10 months ago

      No Genes used

      374 Days

      60 % cure


    • profile image

      Zombies 10 months ago

      535 days 50% cure 16350 points

    • profile image

      Braydon 10 months ago

      510 days, 50% cure and most of the symptoms

    • profile image

      Luc1F3R 11 months ago

      No genes used, 641 days 60% cure

    • profile image

      Humn 11 months ago

      491 days 46%of cure dome

    • profile image

      SmugLittleF*** 11 months ago

      603 days, score is 13980.

      I did it first try.

    • profile image

      Carrie 11 months ago

      NO genes used

      cure at 57%

      killed all of humanity (outside of earthquakes and flooding) in 659 days.

      10/10 would kill humanity again

    • profile image

      MandyLeigh 11 months ago

      Took me 641 days at 56 percent cure rate.

      Had to start in Greenland, because of the boarders closing. I just shaped the cold with the heat. But followed all the same steps.

    • profile image

      Jen 11 months ago

      Got it on my first try...422 days, 30% cure


    • profile image

      Paul Richard 11 months ago

      446 days and 30% cure

    • profile image

      Justin 11 months ago

      YES!!!! I´ve completed it in 576 days with 59% cure research, and it was from my first try! Thanks!

    • profile image

      rappy 11 months ago

      551 days

      51% cure

      15800 pts

      tnx a lot!

    • profile image

      Raven 12 months ago

      Starting in Brazil didn't work for me, Greenland shut down their boarders before anyone got infected, those bastards. However, starting in Greenland and "buying" Heat Resistance I instead of Cold Resistance II worked just fine

    • profile image

      Liz 12 months ago

      577 days

      55% cure

      Score - 11890

      Thank you!

    • profile image

      Ben 12 months ago

      531 days

    • profile image

      Rachel M 12 months ago

      YEESSSS!!!! First try! Thank you so much! I only used one of the genetic modifiers (only had the ionised helix). Finished in 755 days, cure 59%, score 10,740. I've used almost all your tutorials whenever I wanna pull my hair out and you've never let me down. Thanks again :)

    • profile image

      Jason 12 months ago

      Thank you.

      554 days,

      54% cure.

      Total score 15,590.

    • profile image

      Cyan 12 months ago

      498 days, cure = 55% score 16250

    • profile image

      Wes 12 months ago

      607 days

      55% cure

      12620 points

    • profile image

      GloriousFin 12 months ago

      Hello I would like to ask if you have tutorials on how to beat nano-virus w/out genetic modifications? I haven't cashed on the premium yet and I have reached nano-virus w/out genetic modifications until now because of your help.

    • Ashleign profile image

      Ashleign 12 months ago

      Check out my youtube channel I recently did an update to the prion. Haven't yet updated the written tutorial yet. There should be a video that was actually a live stream and did 3 of the tutorials prion was a bit iffy.

    • profile image

      Rivish 12 months ago


      I got this on my first try with no extra genes in the beginning since I haven't purchased the game. The way the cure was flying up in the beginning I thought for sure I wasn't gonna get it, but with your steps I was proven wrong :-)

      603 days

      58% cure

      10850 score

      I've been using all your tutorials so far and the one I had issues with was actually Prion. I did your steps as suggested and the cure kept overriding me. I tweaked up the strategy after several tries and got past it. Couldn't have gotten past all so far without you! Thank you!

    • profile image

      Auriel 12 months ago

      Done in 524 days with cure at 47%

    • profile image

      Kuba 13 months ago

      Wait... I'm have to evolve sneezing when I don't have coughing?