How to Beat Plague Inc. Bio-Weapon on Normal

Updated on April 13, 2016

A Walkthrough of Plague Inc. Bio-Weapon on Normal

The Bio-Weapon on Plague Inc. is certainly an interesting bastard. I have spent the last several days compiling a straightforward guide—you'll find this to be much easier to follow than other guides on the Internet.

Be sure to utilize the genetic codes. If you are playing the free version of this game on your mobile device, be sure to buy the game. At two dollars, it's totally worth it for the additional perks you'll get.

First off, use the following Genetic Codes (they are extremely helpful):

  • Metabolic Hijack
  • Genetic Mimic
  • Native Biome
  • Xerophile
  • Ionized Helix

Infecting on Evolved Bio-Weapon on Normal

  1. Start your Plague in Saudi Arabia.
  2. Build your DNA Points to 10. Abilities: Gene Compression 1, Gene Compression 2, and Deactivate Modified Genes 1.
  3. Build your DNA Points to 15. Abilities: Gene Compression 3
  4. Build your DNA Points to 15. Transmissions: Air 1; Abilities: Nucleic Acid Neutralisation 1
  5. Build your DNA Points to 20. Abilities: Cold Resistance 1; Transmissions: Water 1; Devolve Symptoms for extra points.
  6. Build your DNA Points to 17-20. Abilities: Deactivate Modified Genes 2, Nucleic Acid Neutralisation 2
  7. Build your DNA Points to 10. Symptoms: Cysts, Abscesses.
  8. Build your DNA Points to 20. Abilities: Deactivate Modified Genes 3.
  9. Build your DNA Points to 20. Transmissions: Bird 1.
  10. Build your DNA Points to 30. Abilities: Cold Resistance 2; Symptoms: Coughing.
  11. Build your DNA Points to 50. You can allow your symptoms, but pop cure bubbles. Transmissions: Air 2, Water 2; Abilities: Nucleic Acid Neutralisation 3.
  12. Build your DNA Points to 50. Abilities: Drug Resistance 1, Genetic Hardening 1; Symptoms: Sneezing.
  13. Build your DNA Points to 50. Abilities: Drug Resistance 2.
  14. Wait until everyone is infected. Abilities: Unlock Annihilate Gene.
  15. Kill them all!

Congratulations! You've completed the tutorial for Plague Inc. Evolved Bio-Weapon on normal. My record is 760 days, but if you beat it, I want to know about it. Make sure you post it in the comment section below.

Video: How to Beat Plague Inc. Evolved Bio-Weapon on Normal

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      • profile image

        Maku 

        5 hours ago

        not with Ur way but beat you 710 days :D

      • profile image

        Bobman5 

        30 hours ago

        Me beat you 599 days

      • profile image

        Aperson 

        3 days ago

        646 days for me :)

      • profile image

        binPilzig 

        6 days ago

        650 days

      • profile image

        Azurel 

        6 days ago

        643 days

      • profile image

        Marvin 

        8 days ago

        490 days thanks

      • profile image

        33123 

        10 days ago

        710 days

      • profile image

        Foxized 

        12 days ago

        590 days, thanks man!

      • profile image

        sde 

        2 weeks ago

        600 dats

      • profile image

        Theo 

        2 weeks ago

        590 days thx for tutorial.

      • profile image

        madscientist 

        2 weeks ago

        629 thanks for the tutorial!

      • profile image

        Megan 

        2 weeks ago

        377 days. Used atp boost, aerocyte, genetic mimic, xerophile only. Then I followed the guide.

      • profile image

        Alli 

        2 weeks ago

        I followed this tutorial but I won in 650 days. I used slightly different genes but I followed the tutorial exactly.

      • profile image

        Aboi 

        2 weeks ago

        755 DAYS Bio-Wepon

      • profile image

        Pancho 

        3 weeks ago

        I was laughing like an evil maniac when i flipped the killswitch on this thing, 601 days

      • profile image

        Jon 

        3 weeks ago

        I followed ur tutorial. Only thing different was i deactivated most symptoms (other than ur mentioned ones), unlocked animal blood and rodent transmissions, and maxed out the cure delaying tree once everyone infected. killed everyone in 624 days

      • profile image

        Paula 

        3 weeks ago

        Beat it in only 555 days!

      • profile image

        Nate 

        4 weeks ago

        401 days

        66% cure

        3 genes

        and three biohazard score

      • profile image

        Bighead 

        4 weeks ago

        493 days

      • profile image

        Jack Jacoby 

        4 weeks ago

        659 days no genes

      • profile image

        Connor6456 

        4 weeks ago

        610 days

      • profile image

        randy 

        4 weeks ago

        600 days

      • profile image

        Charlotte 

        4 weeks ago

        636 days! Thank you!

      • profile image

        TopazDragon 

        4 weeks ago

        573 Days

      • profile image

        BluestarCraft 

        5 weeks ago

        679 days

      • profile image

        TT12 

        5 weeks ago

        This worked amazingly well! New record: 693 days! You’re awesome :)

      • profile image

        jack 

        5 weeks ago

        got 655

      • profile image

        Christopher Croce 

        5 weeks ago

        Thanks!!!! Using your tips minus one gene from start..... 565 days following your guide!

      • profile image

        Tommy 

        6 weeks ago

        I beat it in 614 days thanks to you

      • profile image

        Ev 

        6 weeks ago

        581 days!

      • profile image

        Matko 

        6 weeks ago

        592 days

      • profile image

        Cooper 

        6 weeks ago

        Got 600 days

      • profile image

        aa 

        7 weeks ago

        593 days

      • profile image

        Brandon 

        7 weeks ago

        Worked amazingly I beat it yay thanks so much!

      • profile image

        Zoofy 

        7 weeks ago

        I got it in 609 days!!

      • profile image

        MewingMitten 

        8 weeks ago

        121 Days

        3% Cure Progress

        5 Biohazards

        Best thing that happened to me today

      • profile image

        Jack 

        8 weeks ago

        I got it in 617 days :p

      • profile image

        (nobody) 

        8 weeks ago

        I followed your insturctions from bacteria up until bioweapon and they all worked perfectly.

        Thx!

      • profile image

        Kidsroc 

        2 months ago

        72 days 97% cure get coughing and as many infectious symptoms ASAP then go for the kill switch once infected the planet.

      • profile image

        Anonymous 

        2 months ago

        178 0% cure

      • profile image

        [ ] 

        2 months ago

        179 days, 0% cure. have fun catching up kids!

      • profile image

        Hopper806 

        2 months ago

        561 days

        33%complete

        16210 score

      • profile image

        NINJA BOY 

        2 months ago

        HA BEAT 702 DAYS!

      • profile image

        Womb Mother 

        2 months ago

        On normal, 724 days, cure 10%. I skipped anything to do with symptoms, and at the end when I needed DNA, I sold off transmissions. Otherwise, I followed your directions to a T.

      • profile image

        Jake Jameson 

        2 months ago

        580 days

        10% cure

        35,920 score

        Don't bother with symptoms until everyone is infected. Use the ability costs don't increase gene. Start in saudi. Extremeofile gene, red bubble gene, plane bonus gene. Gene comp +2 and cold resis right away, then air/water trans. Do some more abilities to slow plagues killing. Bird and insect trans. Cold 2, drug and genetic harden both +2. Pop a couple more abilities to slow plague, air/water trans 2. Finish off rest of abilities up to the kill switch. All infected and activate. Gene shuffle to get cure low as possible (was at about 25% for me here). And finally evolve to insanity symptom and coma to lower further. Win. Works on Brutal too

      • profile image

        Anorexicturkey 

        2 months ago

        613 days, 26% cure, and 17820 points. No special genes used

      • profile image

        Tat2dDude67 

        2 months ago

        618 days

        Cure 42% complete

        Score 12550

      • profile image

        Name 

        2 months ago

        Well it really works, the cure nearly beats you but that the thing.. you get tons of points in a second. So I just did genetic reshuffle. All 3. Perfect. You get tons of points when most of the world is infected. Yeah, really.

      • profile image

        Zoizax 

        2 months ago

        548 days, 10040 points. With no genes!

        Cure 51%

      • profile image

        Matheus 

        2 months ago

        740 days, 64% cure, 5940 score

      • profile image

        Huan 

        2 months ago

        622 with 50%

      • profile image

        Oof 

        2 months ago

        601 with 55 percent of the cure done

      • profile image

        Cam 

        2 months ago

        635

        is my record

      • profile image

        eycho 

        2 months ago

        647 days 42% cure

      • profile image

        Abn V3num 

        2 months ago

        677 days 53% cure

      • profile image

        amellowcoin 

        2 months ago

        550 days with 53% cure

      • profile image

        Michelle 

        2 months ago

        640 days!

      • profile image

        hannah 

        2 months ago

        442 days with 25% cure

      • profile image

        werp 

        2 months ago

        498 with 20% cure

      • profile image

        FUUUUUUU 

        2 months ago

        THE CURE IS ALWAYS AT 90% BY THE TIME I GET DRUG RESISTANCE 2

      • profile image

        Alcaraz666 

        3 months ago

        579 days, 32% cure, thanks bro!

      • profile image

        Jesus'scure 

        3 months ago

        690 days 30% cure

      • profile image

        Jesus'scure 

        3 months ago

        690 days 30% cure

      • profile image

        Wagamamas 

        3 months ago

        634 days 54% cure

      • profile image

        Foxlovinggirl 

        3 months ago

        631 days

        59% cure

      • profile image

        Callumgrayone 

        3 months ago

        654 days

      • profile image

        SuWoop 

        3 months ago

        562 days

        38% cure

      • profile image

        Yeet 

        3 months ago

        I got to 503 days and my cure was on 43%

      • profile image

        Gundarma 

        3 months ago

        630 days.

        Cure progress 45%

        Score 12120

      • profile image

        I beat your record first try lol 

        3 months ago

        I got it in 663 days

      • profile image

        Arthur 

        3 months ago

        625 days thanks to you man !!

      • profile image

        Rotthier 

        3 months ago

        I'was at 400 days but Greenland killed me, damn u greenland

      • profile image

        Isak Mathiesen 

        3 months ago

        Days: 578

        Cure: 35%

        Score: 13420

      • profile image

        Vanessa Phoenix 

        3 months ago

        610 days for me!

      • profile image

        Jason Fakles 

        3 months ago

        573 days 53% cure

      • profile image

        Allison 

        3 months ago

        I got 693 days. After the Annihilate Gene I had to do Genetic Shuffle twice cause cure was moving fast.

      • profile image

        Russell 

        3 months ago

        606 days with 35% cure

      • profile image

        Hayes Causey 

        3 months ago

        I got 639 days. I got most of the really lethal symptoms after Annilhilate, don’t know if affected the lethality, as the annilhilate brings the bar to full anyway

      • profile image

        Lenin 

        3 months ago

        649 days 62%cure

      • profile image

        Shannon 

        3 months ago

        Did it 563 62% cure progress. These walkthroughs have been saving me from chucking my phone lol

      • profile image

        Auden Browne 

        3 months ago

        Ashleign has taught me how to win all but two of the disease types. I just wanted to say thanks.

      • profile image

        Anonymous 

        3 months ago

        579 days

        Unlocked total organ failure after following the steps

      • profile image

        derp 

        3 months ago

        663 days. had to sell all my symptoms and stuff to get the cure off my back though.

      • profile image

        Candor 

        3 months ago

        Beat it in 664 days, anyone do better?

      • profile image

        Louis 

        3 months ago

        595 with 23% cure

      • profile image

        greg 

        3 months ago

        559 same as you wrote it up

      • profile image

        Ethan Young 

        3 months ago

        I did it in 649 days. I just bought lethal symptoms after everyone was infected.

      • profile image

        Megan Riddle 

        3 months ago

        609 days with a 33% cure. I find using the ability to pop cure bubbles for points helps more

      • profile image

        Chris 

        3 months ago

        537 days with 36% cure. Instead waiting to accumulate the DNA, I just waited till I had enough for the next upgrade which probably sped things up a bit. I also carried on upgrading symtoms after the annihilate gene to destroy cure progress and speed up the end.

      • profile image

        Grae 

        3 months ago

        39% Cure at 629 Day!

        Great tutorial as always! 100% effective for me!

      • profile image

        Chili-7 

        3 months ago

        Does not work; Greenland was never infected, and by the time it was, the cure was at 100%. 653 days, Chili-7 was eradicated. Rip

      • profile image

        Madisyn Rooke 

        4 months ago

        My current record is 597 days with only a 40% cure rate

      • profile image

        Jonez 

        4 months ago

        It took me only 605 days lol

      • profile image

        Fed 

        4 months ago

        654 days, thank you!

      • profile image

        that Jellyfish tho 

        4 months ago

        707 days

      • profile image

        anon 

        4 months ago

        568 days

      • profile image

        Anon 

        4 months ago

        676 days

      • profile image

        Anonymous 

        4 months ago

        678 days

      • profile image

        Gary 

        4 months ago

        602 days

      • profile image

        PA 

        4 months ago

        603. i added environmental hardening.

      working

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