How to Beat Plague Inc. Bio-Weapon on Normal

Updated on April 13, 2016

A Walkthrough of Plague Inc. Bio-Weapon on Normal

The Bio-Weapon on Plague Inc. is certainly an interesting bastard. I have spent the last several days compiling a straightforward guide—you'll find this to be much easier to follow than other guides on the Internet.

Be sure to utilize the genetic codes. If you are playing the free version of this game on your mobile device, be sure to buy the game. At two dollars, it's totally worth it for the additional perks you'll get.

First off, use the following Genetic Codes (they are extremely helpful):

  • Metabolic Hijack
  • Genetic Mimic
  • Native Biome
  • Xerophile
  • Ionized Helix

Infecting on Evolved Bio-Weapon on Normal

  1. Start your Plague in Saudi Arabia.
  2. Build your DNA Points to 10. Abilities: Gene Compression 1, Gene Compression 2, and Deactivate Modified Genes 1.
  3. Build your DNA Points to 15. Abilities: Gene Compression 3
  4. Build your DNA Points to 15. Transmissions: Air 1; Abilities: Nucleic Acid Neutralisation 1
  5. Build your DNA Points to 20. Abilities: Cold Resistance 1; Transmissions: Water 1; Devolve Symptoms for extra points.
  6. Build your DNA Points to 17-20. Abilities: Deactivate Modified Genes 2, Nucleic Acid Neutralisation 2
  7. Build your DNA Points to 10. Symptoms: Cysts, Abscesses.
  8. Build your DNA Points to 20. Abilities: Deactivate Modified Genes 3.
  9. Build your DNA Points to 20. Transmissions: Bird 1.
  10. Build your DNA Points to 30. Abilities: Cold Resistance 2; Symptoms: Coughing.
  11. Build your DNA Points to 50. You can allow your symptoms, but pop cure bubbles. Transmissions: Air 2, Water 2; Abilities: Nucleic Acid Neutralisation 3.
  12. Build your DNA Points to 50. Abilities: Drug Resistance 1, Genetic Hardening 1; Symptoms: Sneezing.
  13. Build your DNA Points to 50. Abilities: Drug Resistance 2.
  14. Wait until everyone is infected. Abilities: Unlock Annihilate Gene.
  15. Kill them all!

Congratulations! You've completed the tutorial for Plague Inc. Evolved Bio-Weapon on normal. My record is 760 days, but if you beat it, I want to know about it. Make sure you post it in the comment section below.

Video: How to Beat Plague Inc. Evolved Bio-Weapon on Normal

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      • profile image

        Brandon 

        7 hours ago

        Worked amazingly I beat it yay thanks so much!

      • profile image

        Zoofy 

        8 hours ago

        I got it in 609 days!!

      • profile image

        MewingMitten 

        2 days ago

        121 Days

        3% Cure Progress

        5 Biohazards

        Best thing that happened to me today

      • profile image

        Jack 

        4 days ago

        I got it in 617 days :p

      • profile image

        (nobody) 

        4 days ago

        I followed your insturctions from bacteria up until bioweapon and they all worked perfectly.

        Thx!

      • profile image

        Kidsroc 

        6 days ago

        72 days 97% cure get coughing and as many infectious symptoms ASAP then go for the kill switch once infected the planet.

      • profile image

        Anonymous 

        7 days ago

        178 0% cure

      • profile image

        [ ] 

        8 days ago

        179 days, 0% cure. have fun catching up kids!

      • profile image

        Hopper806 

        10 days ago

        561 days

        33%complete

        16210 score

      • profile image

        NINJA BOY 

        2 weeks ago

        HA BEAT 702 DAYS!

      • profile image

        Womb Mother 

        2 weeks ago

        On normal, 724 days, cure 10%. I skipped anything to do with symptoms, and at the end when I needed DNA, I sold off transmissions. Otherwise, I followed your directions to a T.

      • profile image

        Jake Jameson 

        2 weeks ago

        580 days

        10% cure

        35,920 score

        Don't bother with symptoms until everyone is infected. Use the ability costs don't increase gene. Start in saudi. Extremeofile gene, red bubble gene, plane bonus gene. Gene comp +2 and cold resis right away, then air/water trans. Do some more abilities to slow plagues killing. Bird and insect trans. Cold 2, drug and genetic harden both +2. Pop a couple more abilities to slow plague, air/water trans 2. Finish off rest of abilities up to the kill switch. All infected and activate. Gene shuffle to get cure low as possible (was at about 25% for me here). And finally evolve to insanity symptom and coma to lower further. Win. Works on Brutal too

      • profile image

        Anorexicturkey 

        2 weeks ago

        613 days, 26% cure, and 17820 points. No special genes used

      • profile image

        Tat2dDude67 

        2 weeks ago

        618 days

        Cure 42% complete

        Score 12550

      • profile image

        Name 

        2 weeks ago

        Well it really works, the cure nearly beats you but that the thing.. you get tons of points in a second. So I just did genetic reshuffle. All 3. Perfect. You get tons of points when most of the world is infected. Yeah, really.

      • profile image

        Zoizax 

        2 weeks ago

        548 days, 10040 points. With no genes!

        Cure 51%

      • profile image

        Matheus 

        2 weeks ago

        740 days, 64% cure, 5940 score

      • profile image

        Huan 

        3 weeks ago

        622 with 50%

      • profile image

        Oof 

        3 weeks ago

        601 with 55 percent of the cure done

      • profile image

        Cam 

        3 weeks ago

        635

        is my record

      • profile image

        eycho 

        3 weeks ago

        647 days 42% cure

      • profile image

        Abn V3num 

        4 weeks ago

        677 days 53% cure

      • profile image

        amellowcoin 

        4 weeks ago

        550 days with 53% cure

      • profile image

        Michelle 

        4 weeks ago

        640 days!

      • profile image

        hannah 

        5 weeks ago

        442 days with 25% cure

      • profile image

        werp 

        5 weeks ago

        498 with 20% cure

      • profile image

        FUUUUUUU 

        5 weeks ago

        THE CURE IS ALWAYS AT 90% BY THE TIME I GET DRUG RESISTANCE 2

      • profile image

        Alcaraz666 

        5 weeks ago

        579 days, 32% cure, thanks bro!

      • profile image

        Jesus'scure 

        5 weeks ago

        690 days 30% cure

      • profile image

        Jesus'scure 

        5 weeks ago

        690 days 30% cure

      • profile image

        Wagamamas 

        5 weeks ago

        634 days 54% cure

      • profile image

        Foxlovinggirl 

        5 weeks ago

        631 days

        59% cure

      • profile image

        Callumgrayone 

        5 weeks ago

        654 days

      • profile image

        SuWoop 

        6 weeks ago

        562 days

        38% cure

      • profile image

        Yeet 

        6 weeks ago

        I got to 503 days and my cure was on 43%

      • profile image

        Gundarma 

        6 weeks ago

        630 days.

        Cure progress 45%

        Score 12120

      • profile image

        I beat your record first try lol 

        6 weeks ago

        I got it in 663 days

      • profile image

        Arthur 

        6 weeks ago

        625 days thanks to you man !!

      • profile image

        Rotthier 

        6 weeks ago

        I'was at 400 days but Greenland killed me, damn u greenland

      • profile image

        Isak Mathiesen 

        6 weeks ago

        Days: 578

        Cure: 35%

        Score: 13420

      • profile image

        Vanessa Phoenix 

        6 weeks ago

        610 days for me!

      • profile image

        Jason Fakles 

        7 weeks ago

        573 days 53% cure

      • profile image

        Allison 

        7 weeks ago

        I got 693 days. After the Annihilate Gene I had to do Genetic Shuffle twice cause cure was moving fast.

      • profile image

        Russell 

        7 weeks ago

        606 days with 35% cure

      • profile image

        Hayes Causey 

        7 weeks ago

        I got 639 days. I got most of the really lethal symptoms after Annilhilate, don’t know if affected the lethality, as the annilhilate brings the bar to full anyway

      • profile image

        Lenin 

        7 weeks ago

        649 days 62%cure

      • profile image

        Shannon 

        7 weeks ago

        Did it 563 62% cure progress. These walkthroughs have been saving me from chucking my phone lol

      • profile image

        Auden Browne 

        8 weeks ago

        Ashleign has taught me how to win all but two of the disease types. I just wanted to say thanks.

      • profile image

        Anonymous 

        8 weeks ago

        579 days

        Unlocked total organ failure after following the steps

      • profile image

        derp 

        8 weeks ago

        663 days. had to sell all my symptoms and stuff to get the cure off my back though.

      • profile image

        Candor 

        8 weeks ago

        Beat it in 664 days, anyone do better?

      • profile image

        Louis 

        8 weeks ago

        595 with 23% cure

      • profile image

        greg 

        2 months ago

        559 same as you wrote it up

      • profile image

        Ethan Young 

        2 months ago

        I did it in 649 days. I just bought lethal symptoms after everyone was infected.

      • profile image

        Megan Riddle 

        2 months ago

        609 days with a 33% cure. I find using the ability to pop cure bubbles for points helps more

      • profile image

        Chris 

        2 months ago

        537 days with 36% cure. Instead waiting to accumulate the DNA, I just waited till I had enough for the next upgrade which probably sped things up a bit. I also carried on upgrading symtoms after the annihilate gene to destroy cure progress and speed up the end.

      • profile image

        Grae 

        2 months ago

        39% Cure at 629 Day!

        Great tutorial as always! 100% effective for me!

      • profile image

        Chili-7 

        2 months ago

        Does not work; Greenland was never infected, and by the time it was, the cure was at 100%. 653 days, Chili-7 was eradicated. Rip

      • profile image

        Madisyn Rooke 

        2 months ago

        My current record is 597 days with only a 40% cure rate

      • profile image

        Jonez 

        2 months ago

        It took me only 605 days lol

      • profile image

        Fed 

        2 months ago

        654 days, thank you!

      • profile image

        that Jellyfish tho 

        2 months ago

        707 days

      • profile image

        anon 

        2 months ago

        568 days

      • profile image

        Anon 

        2 months ago

        676 days

      • profile image

        Anonymous 

        2 months ago

        678 days

      • profile image

        Gary 

        2 months ago

        602 days

      • profile image

        PA 

        2 months ago

        603. i added environmental hardening.

      • profile image

        Kit 

        2 months ago

        666 days!

      • profile image

        Random Human 

        2 months ago

        I got this in 431 days. I used the same strategy.

      • profile image

        Existential Crisis 

        2 months ago

        672 days! Thanks for the tutorials!

      • profile image

        Yari Bins 

        2 months ago

        716 days thanks I couldn't have done it without you

      • profile image

        Rick 

        2 months ago

        590 days with 33% cure

      • profile image

        Haha 

        2 months ago

        Im 1 day faster

      • profile image

        george 

        2 months ago

        621 days

      • profile image

        Mil73 

        2 months ago

        583 days with 52% cure and like 50 points left

      • profile image

        gg ez 

        2 months ago

        under 600 days, good guide

      • profile image

        Isopropyl 

        2 months ago

        630 days & 63% cure research

      • profile image

        Jitterbug 

        2 months ago

        I did it in 419 days!

      • profile image

        ASDASD 

        2 months ago

        599 days

        69% cure

        9470

        my only change was using the genetic code letting the blue science bubbles worth 4 DNA

      • profile image

        Aaron 

        2 months ago

        601 days

        Cure 68%

        Score 7960

      • profile image

        joe 

        2 months ago

        589 days, 60% cure, 7290 score

      • profile image

        Basil 

        2 months ago

        639 days.. 50% cure ..8910 score

      • profile image

        Stan 

        2 months ago

        580 days, 9980 score, 31% cure

      • profile image

        Cp 

        2 months ago

        634 days, 7230 score, 52 cure

      • profile image

        Creeperr 

        2 months ago

        I maked in 649 days and I have 7560 Score

      • profile image

        Mk 

        2 months ago

        658 days 43% cure

      • profile image

        Tanya Pakla 

        2 months ago

        560 days and 69% cure

      • profile image

        Beat yall 

        2 months ago

        631 days baby!!

      • profile image

        Racinky88 

        2 months ago

        602 days

        39% cure

        Score 12360

      • profile image

        AKLIFE 

        2 months ago

        562 days 4% cure

      • profile image

        Goodpie2 

        2 months ago

        You dedicate waaaay too much effort on gene compression early in the game, and consequently lose the ability to use it later. I didn't buy it for the first time until my first death, and beat it in 584 days.

      • profile image

        DuplexLamp18297 

        2 months ago

        517 days and 18% on cure

      • profile image

        2 months ago

        684 days :)

      • profile image

        Baller69 

        2 months ago

        I beat it in 706 which is 54 days better than u. Get rekt.

      • profile image

        Thomas 

        2 months ago

        478 days

        Namned; Death

      • profile image

        Blake 

        2 months ago

        Mine lasted 672 days and I followed this exactly

      • profile image

        Anonymous 

        2 months ago

        636 days

        37% Cure

      • profile image

        Jbates 

        2 months ago

        552 days

      • profile image

        Steph 

        2 months ago

        685 days, cure progress 21%

      • profile image

        NameNotCow 

        2 months ago

        461 Days

        25% Cure

        Started in India

      working

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