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"Plague Inc. Evolved": Simian Flu on Normal

Ashleign is a woodworker and yard enthusiast. She can be found as enthusiast.mysticalnerdtv on Instagram and mysticalnerd on Twitch.


Take Your Stinking Paws Off Me, You Damned Dirty Ape!

So it seems like yesterday I crawled out bed and ran downstairs at 10pm at night to see my father watching Planet of the Apes. Of course, back then we had this ancient technology called VHS. Kids today of course have no idea what that is, unless their parents were 80's babies and still have old copies of the Lion King.

No the day of recording over crappy movies to record all your favorite shows is over unfortunately. With the end of VHS and the move into DVD which will soon be replaced by BluRay or whatever else those squirrelheaded tech gurus over in silicon valley come up with next.

Here we have the Simian Flu, a plague that you will want to start in the Country of Indonesia.

This one is a lot different than the others. I am just going to let you know, you may encounter a moderate amount of BS in this tutorial.

Take a Deep Breath

Let's get this thing started here guys. We are venturing into unknown territory. Plague Inc is renowned for its casual gameplay style. Not anymore. Simian Flu is going to take some serious attention and ability to react quickly.

Allow all Symptom mutations except: Neuro-Enhancement 1 and except: Lethal Symptoms

Our Mission:

Infect the entire world. Allow Apes to take over. Kill the entire world. Sounds simple right? Wrong.

Start in Indonesia

Build your DNA Points to (20)


  • Simian Neuro-Genesis
  • Organised Travel

Build your DNA Points to (15)

Scroll to Continue

Read More From Levelskip


  • Ape Colonies

Use Your Ape Colony ability on Indonesia

Build your DNA Points to (16)


  • Cognitive Shift
  • Ape Rampage

Build your DNA Points to (30)


  • Fomites 1
  • Fomites 2


  • Cold Resistance 1

Once Indonesia's Ape Colony Bar is full, use Migration to move them to another country. (doesn't matter which)

Create another Colony in another Country (Doesn't matter which just not Indonesia)

Build your DNA Points to (40)


  • Education
  • Drug Resistance 1
  • Transmissions:
  • Inter-Genus Dissemination 1

Create another Colony in another country (Doesn't matter which)

Build your DNA Points to (50)


  • Fomites 3
  • Air 1
  • Water 1
  • Sebaceous Excretion

Build your DNA Points to (60)


  • Primal Awareness
  • War Paint
  • Logistics
  • Horseback Riding

This would be a good time to pause your game and move your colonies around. You want to spread them across the map. (This is for when the research facilities come into play) Spread them out but not too far apart.

Unpause your game.

You should see any moment now, little grey cure blocks they will have a beaker on them.

Build your DNA Points to (80)


  • Hominidae Bridge
  • Air 2
  • Water 2

Now, use your little fist or (Ape Rampage) on any grey cure countries. If you cannot use the little fist, migrate a colony to that country and try again.

Build your DNA Points to (75)

(Global Action Message should have come up by now)


  • Primal Hunt
  • Weapon Creation
  • Cold Resistance 2

If you encounter drones, or new research facilities, pause your game, Migrate from drones, or use the little fist on the research facilities. Don't forget to unpause your game.

Keep watching for the lethal symptoms, you don't want it to be too lethal before everyone is infected.

Continue to look around the map for cure/research facilities, they will keep coming.


Once you receive the "There are no healthy people left in the world message" Use your DNA points in Symptoms to make it as deadly as possible. Continue to use your DNA points, you will have tons and tons of them to do this.

Remember, Keep migrating out of drone strikes and keep destroying those research/cure facilities.

In the next several minutes you will be migrating and destroying research facilities. It is very easy to lose track of the cure progress. Just remember to pause the game if things get out of hand.


Apes have taken over and the Humans are dead!

It took me roughly 1000 days to complete the tutorial, How long did it take you?

I want to know if you mixed it up a little or if you have an easier way. Leave a comment below.


Leave a Comment With...

The amount of days it took you to win. I wanna know.

Planet of the Apes Trivia

For each question, choose the best answer. The answer key is below.

  1. What year did the original Planet of the Apes movie come out?
    • 1968
    • 1988
    • 1948
    • 1978
  2. Who coined the phrase "Take your stinking paws off me, you damned dirty ape."
    • Scarlett Johansson
    • Shia LaBeouf
    • Charlton Heston
    • Tom Hanks
  3. What is Planet of the Apes about?
    • Giant Turtles take over the earth and only apes have the know-how to destroy them.
    • An astronaut travels through time and Apes have taken over the world.
    • An astronaut travels through time and David Bowie has a cult that has taken over the world.
    • The starship enterprise travels through the Game of Thrones wormhole, and find an Ape floating in space.

Answer Key

  1. 1968
  2. Charlton Heston
  3. An astronaut travels through time and Apes have taken over the world.

© 2014 Ashleign


ori on August 23, 2020:

not even 900 days

Taylor Tomlinson on July 02, 2020:

I never saw any drones, and only had 1 research facility, and it was nearthe very beginning. It is very confusing indeed how this all works, but the tutorial worked wonders. Thanks.

Quintavius williams on March 10, 2020:

1274 days

Followed each step

Cure progress 36%

All 5 biohazards

Score 144460

MRJ1997 on February 29, 2020:

1,084 days, 26% cure progress, and 209,960 score. First try.

Sodax on February 25, 2020:

958 days, 39% cure, 154600 score on this strat (first try on norm) it's rly good c:

Hellno15 on February 08, 2020:

1007 days with 45% cure and 68490 score

ekil12/Nekiś on January 24, 2020:

966 days, 43% cure, 57920 score

Erick on January 01, 2020:

1342 days

Idris on October 11, 2019:


Ashlynn Stowe on September 27, 2019:

1133 Days, 20% cure, 5/5 biohazards and 247610 score. First time trying and beat it!!!

VincentVMarshburn on August 31, 2019:

Fantastic guide. I followed it to the letter and won on the first try. I think this was my favorite plague. (Tip:don't forget to devolve those lethal symptoms.)

1337 day (I am serious; I have the screenshot to prove it)

44% cure

90400 score

4 biohazards

Genes: Metabolic Hijack, Native Biome, Extremophile

Deane on July 06, 2019:


Near the end I evolved the full path of neural enhancement and created a planet of the apes

Jerome L Zaha on June 11, 2019:

1456. Humans die. 77% cure. But the first time I beat it. Thanks

Donk on March 16, 2019:

Couldn't follow the guide exactly because the stupid lethal mutations kept happening, but I just stopped looking at the guide after the horseback riding and i just winged it from there, but I beat it in 1196 days and it works great, thanks

Countrybass70 on March 03, 2019:

Took longer than 1000 days.

1508 Days

14% Cure

237860 total score

Also I gave it a stupid name, "Monkey Time"

will on March 02, 2019:

using this guide i got 970 days

meilan on February 28, 2019:

I managed to beat Simian Flu on Brutal with this guide! Works perfectly. Thank you!!!

Effigy on November 09, 2018:

Great guide! Siemian Plague has been kicking my butt for a while now. It took 1113 days to complete the game and not one research facility spawned.

Jayne on September 12, 2018:

Time: 840 days

Cure progress: 22%

Score: 40390

Used Metabolic Hijack, suppression and extremophile.

Jacob on August 21, 2018:

991 days 82770 score with this tut ty

Bronzeborg on August 20, 2018:

stupid neuro enhancer keeps evolving for me... once twice in a row! had to spend 50 points to devolve it.

Boi on July 13, 2018:

Took me 1988 days

Blacephalon on July 07, 2018:

me: sees tutorial to start in Indonesia

*internal, but extremely high mental excitement*

dude. I live in Indonesia.

Eric on July 02, 2018:

Wow- this worked incredibly well. I've played it through several times, and this time I racked up a score of 207480, and wiped out humanity in 1063 days.

Unknown on June 10, 2018:

Thank you very much for your tutoriel it really helped me

Calliare on June 10, 2018:

Yes it does work lol

You must be doing something wrong if it failed for you. This is literally the best guide there is.

Ethan Marcello on May 24, 2018:


It does not work at all.

Apparently I need to keep my eye on the cure and somehow get DNA points out of nowhere to by reshuffles and hardening on top of your crap guide. I tried it 8 times and it did not work.

L Bigelow on March 30, 2018:

1017 days, score 61,000, 4 biohazard, cure progress 19%... Named it CHPotA 13 (Charlton Heston Planet of the Apes 13... hehe) followed ur guide to the letter and it was easy, once it had infected everyone, made it as lethal as possible ASAP. I had to VERY proactively run from drones and destroy research facilities as soon as they cropped up. had to pause a lot so it didn't get away from me. Thanks for the guide, helped me thru this one and necroa virus

Lachlan on February 20, 2018:

Took me 1068 days with 27% cure completion and a score total of 122740

Ashleign (author) on January 25, 2018:

I try not to make recommendations, the reason I chose to do this without them, is that not everyone has them unlocked. Metabolic HiJack is my favorite because I am lazy.