Ten Ways to Get More Items in “The Binding of Isaac: Rebirth”

Eric loves to play "The Binding of Isaac: Rebirth" on Steam, and it is one of his favorite games. He wants to teach others about the game.

You Need Items to Win!

There are multiple ways to get items in The Binding of Isaac: Rebirth, and there are many items to find.

In this guide, I will give ten simple things you can do to get more items every time you play the game.

This guide is for beginners. So I won't get too advanced.

Go into every treasure room you can. You can get at six items every run this way.

The first treasure room is always unlocked. You will need at least five keys to open the other doors.

Getting and holding on to five keys should be one of your main priorities early game.

You can get six items from beating bosses before fighting Mom. You can get one more item from the first womb floor.

You can also sometimes get items from fighting optional mini-bosses.

Open every chest you can. You can get items from gold, red, holy, and stone chests.

Each chest type has a separate item pool. I recommend checking the wiki to learn what items each chest gives.

Buying items in the stores is an easy way to get extra items. There are at least six shops every run.

Most items cost 15 coins. Items can be on sale for seven coins.

Secret rooms sometimes can have a single item in them. Super secret rooms can have chests. Sometimes you will find items this way.

Challenge rooms can have chests that have items in them. Sometimes they will have a single item you can take.

Curse rooms are a bit of a risk. They can have many things in them, and they often will be a waste of time.

But rarely they will have items in them. Or red chests that have items.

Both devil and angel rooms will always have some items.

The chances of getting into both rooms are somewhat complicated, and I recommend reading about both on the wiki.

Devil rooms have items that cost health that tend to be more offensive based. Angel room items are free and tend to be more defensive.

Angel rooms are much less riskier to use more often.

There are multiple types of beggars in the game. Each one has a chance of giving you items.

You can give them coins, health, bombs, and keys.

Devil beggars are the most useful, but they are the riskiest to use as well.

Multiple objects in the game can give items when destroyed. The chances of getting items this way are pretty low, but it is worth considering.

You can get items from destroying tinted rocks, urns, skulls, mushrooms, and Polyps.

You can also rarely find craw spaces by destroying normal rocks. Crawl spaces will often have items in them.