How to Beat Plague Inc. Nano-Virus on Normal

Updated on March 11, 2015

Plague Inc.'s Nano-Virus

Plague Inc.'s Nano-Virus is a pesky little bugger. It took me two weeks to build this tutorial and I have finally done it. It is a hard level, so if you don't get it the first time, don't worry. I do apologize. I have done it twice now and used a few genetic codes this time to make it a little easier and faster. This method will work if you do the same. Good luck!

Start your Nano-Virus with the following genes:

  • Metabolic Hijack (Optional)
  • Genetic Mimic
  • Aquacyte
  • Extremophile
  • Ionised Helix

Note: This plague is kind of tough. Keep in mind firstly that you'll need to allow your symptoms except insomnia.

  1. Start your plague in Brazil.
  2. Build your DNA points to 5. Abilities: Code Fragment Interception.
  3. Build your DNA points to 10. Transmissions: Water 1; Symptoms: Cysts.
  4. Build your DNA points to 10. Abilities: Code Segment Interception; Symptoms: Abscesses.
  5. Build your DNA points to 10. Transmissions: Insect 1.
  6. Build your DNA points to 10. Abilities: Radical Elements Stabilised.
  7. Build your DNA points to 10. Abilities: Cold Resistance 1.
  8. Build your DNA points to 15. Abilities: Drug Resistance 1.
  9. Build your DNA points to 15. Transmissions: Bird 1.
  10. Build your DNA points to 25. Abilities: Encryption Breached, Genetic Hardening 1.
  11. Build your DNA points to 20. Abilities: Genetic Reshuffle 1; Symptoms: Sneezing.
  12. Build your DNA points to 30. Abilities: Cold Resistance 2.
  13. Build your DNA points to 18-20. Transmissions: Water 2.
  14. Build your DNA points to 20. Abilities: Genetic Reshuffle 2.
  15. Build your DNA points to 35. Transmissions: Insect 2; Symptoms: Fever.
  16. Build your DNA points to 60. Abilities: Genetic Reshuffle 3, Genetic Hardening 2; Symptoms: Skin Lesions.
  17. Devolve any uber deadly symptoms that may evolve until everyone is infected.
  18. Build your DNA points to 100. Symptoms: Insomnia, Paranoia, Inflammation, Paralysis.
  19. Wait until everyone is infected or very close, then use the deadliest symptoms to start murdering your people.

Be sure to like and comment. I want to know how fast you killed everyone!

Video: Plague Inc. Evolved Nano-Virus Normal Walkthrough

About the Author

Hey guys, I'm ChillBilly aka Ashleign. I have been playing video games for more than 20 years. I enjoy a good bit of strategy style games mixed with online economies. MMOs are my specialty, but I do enjoy all kinds of games. My experience with Plague Inc. started when I picked up the game on my mobile phone. I immediately was hooked due to a long interest I have had in biology. I posted my first tutorial here on HubPages and it was so popular that I decided to make more.

I love helping people, and when I receive good comments and compliments, I feel that I have accomplished something. Please let me know what you thought of this tutorial in the comments below!

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      • profile image

        Twinkie 3 days ago

        I killed everyone in 578 days! Fastest time for any disease I have played! Thanks a lot, Ashleign.

      • profile image

        3 days ago

        512 days

      • profile image

        Kailee 4 days ago

        i killed everyone in 600 days yeet

      • profile image

        Me 5 days ago

        Thank you so much! I'm new at playing Plague so your tutorials are VERY helpful

      • profile image

        Brez 6 days ago

        545 Days

      • profile image

        Gabriel 9 days ago

        Managed to take everyone out in 592 days, my fastest so far.

      • profile image

        Pt0 9 days ago

        Country: UK

        Time: 534 days

        Cure: 57%

        Score: 14620

        I followed your intructions however I didn't use the startup genes and I regressed the cure progress when it was getting too high.

      • profile image

        Juno 11 days ago

        Time: 537 days

        Cure: 50%

        After following up the walkthrough, I’ve chosen to put the extra dna points to total organ failure and necrosis.

      • profile image

        aaaaa 12 days ago

        it only took 549 days lmaoooo

      • profile image

        Some Girl 2 weeks ago

        Time: 553 Days

        Cure: 51% Done

        Score: 16220

      • profile image

        Yay 3 weeks ago

        Thank you!

      • SarahPants profile image

        Sarah Pants 4 weeks ago from Lake Stevens, WA

        I accidentally did air one and two but I beat it in 602 days and 51% cure. Thanks for the help!!!

      • profile image

        Vincenr 6 weeks ago

        Destroyed humanity in 579 days with your strategy.. Thank you

      • profile image

        Antonella 8 weeks ago

        Also wanted to tell you that it worked for me without genetic enhancements.

      • profile image

        Antonella 8 weeks ago

        Yes. Me again. This one worked for me really well. When they started working on the cure inmediately I thought I was screwed, but it stopped at 56% and I was like... WOOHOO!

        I got over 11000 points and 3 hazard symbols!

      • profile image

        Jayden 8 weeks ago

        Wow dude thanks I dont have any of the genes for it

      • profile image

        Sarah 2 months ago

        Omg thank you been stuck on this for a while!!!

      • profile image

        Ram 2 months ago

        Thanks buddy

      • profile image

        L Bigelow 2 months ago

        428 days, cure progress 29%, 3 biohazards with 8030 points, was worried early on when the virus was immediately noticed and the cure began but following ur tutorial, that was no issue, the 3 genetic reshuffles kept those pesky researchers guessing not to mention the genetic hardening. Thanks again

      • profile image

        Timur Liplijn 2 months ago

        Killed all in 447 days thanks i got here with ur tutorials.

      • profile image

        N/A 2 months ago

        The cure didnt even reach half way! (42%)

      • profile image

        n/a 3 months ago

        Worked Great! Won in 593 days, the cure was 52% complete, with a total score of 13060!

      • profile image

        TheAceAttorney1277 3 months ago

        633 days, thanks a lot! :3

      • profile image

        Rachel Rowe 3 months ago


        % 50 cure

      • profile image

        Swag21 3 months ago

        551 Days

        51% Cure

        14460 Score

      • profile image

        Anonymous 4 months ago

        654 days

        61% Cure


      • profile image

        Kenz 4 months ago

        505 days

        50% cure


      • profile image

        Felecia 4 months ago

        560 Days

        57% Cure


      • profile image

        Chris boyst 4 months ago

        493 days



      • profile image

        Mink 5 months ago

        581 days

        50% cured


      • profile image

        Hipkkier162 5 months ago

        Killed everyone but Greenland

      • profile image

        Nate 5 months ago

        576 days

        No genes

        56% cure

        Game crashed before I could see the score...

      • profile image

        Brayden 5 months ago




      • profile image

        Devin 5 months ago

        546 days...53% cure progress... 17370 score

      • profile image

        Aria 5 months ago

        651 days

        Cure Progress: 53%

        Used no genes.

        Strayed off the toutorial at devolve any uber deadly symptoms.

      • profile image

        Darren 4774 6 months ago

        574 days, no genes, 61% cure

      • profile image

        Assemblers 6 months ago

        Killed everyone in 620 days!!! Thank you!!!

      • profile image

        EpicGrimm 6 months ago

        Been using your tuts to get thru everything on normal, as I always get symptom happy too early. Lol :) but here ya go:

        Time: 601 Days

        Cure Progress: 49%

        Score: 14010

      • profile image

        Tompie 6 months ago

        I love this website it has helped me with a lot more than just the nano virus!!

      • profile image

        Darrin 6 months ago

        628 days 50% thanks

      • profile image

        Dustin 6 months ago

        I won in 592 days

      • profile image

        uchboy 6 months ago

        601 days cure 57% score 13460

      • profile image

        Neryma921 6 months ago

        627 days! Cure @ 53% score 9730!!

      • profile image

        Ladislaus 6 months ago

        578 days and 90%

      • profile image

        Kimmy 6 months ago

        578 days, cure 52%

        I forgot the score.

        I didn't use any genes either.

      • profile image

        Xavier Ramirez 7 months ago

        Its easy, the special genes aren't that important, but they're useful.and I succeeded first try, along with the prion and fungus!!!

      • profile image

        Aldones 7 months ago

        If you need the correct genes, just do a few casual runs to accumulate most of them. I was able to use this guide without all the required genes, using the best ones I had.

      • profile image

        TKT 7 months ago

        Your other tutorials were exstreamly helpful, however I cannot do this one because I don't have the right genes. Please can you update this tutorial so you don't have to use genes

      • profile image

        Transpoin 7 months ago

        479 days, cure 44%, 20790 final score

      • profile image

        Hope 7 months ago

        594 days, 57% cure, 12910 final score. Thanks fam I've been stuck on this for a few weeks.

      • profile image

        Alix 7 months ago

        Only took 671 days to wipe out humanity

      • profile image

        Geoff KCMO 7 months ago

        700 days...58% cure 9670 pts. Allowed some extra points to accrue, but nice tutorial...speed up ftime for eradication by throwing all symptoms into the mix.

      • profile image

        Henta 7 months ago

        740 Days with 68% cure

      • profile image

        Jacob 7 months ago

        Days: 599

        Cure: 59%

        DNA Sequence: Complex

        Score Total: 11950

      • profile image

        Liljja Winther 7 months ago

        Thank you so much! Killed everyone in 548 days on my try. They fought bravely but only got the cure up to 52%.

      • profile image

        Grady 7 months ago

        I wiped out the earth with the nano virus in 618 days

      • profile image

        david 7 months ago

        Started in India, 450 days, Cure 34% , Points 16320

      • profile image

        Kelly 8 months ago

        546 Days / Cure 55% / 14060 points

        I was having so much trouble with the nano virus on my own. Thank you so much for the guide! You're an evil genius :)

      • profile image

        smhailey 8 months ago

        I used your guide to beat the Nano-Virus. It took me 578 days (57% cure & 13,300 points). I only have 6 genes unlocked (thanks to your guides) so I used the following: ATP Boost, Travel Genes, Ionised Helix, Darwinist, & Xerophile. Thanks again for writing these guides. I’m learning a ton about this game.

      • profile image

        Cat lover 8 months ago

        414 days it went by fast thanks for the tips!

      • profile image

        Cat 07 9 months ago

        548 days

        51% cure

        13130 points

      • profile image

        Jeff 9 months ago




        Ashleigh awesomeness-110%

      • profile image

        Bido 9 months ago

        Started in India instead of Brazil still worked great, 737days, 60%cure, love your tutorials, thanks

      • profile image

        Anshul Agrawal 9 months ago


        Cure 58%

        Points 12470

      • profile image

        Hanbanan 9 months ago

        609 days 55% cure!

      • profile image

        Hii 9 months ago

        522 days, with none of the extra genes!

      • profile image

        Ryan 9 months ago

        Killed in 614 days, 112 DNA left, cure at 58%

      • profile image

        sara 9 months ago

        killed everyone in 682, cure 55% 107 dna

      • profile image

        AmiTo 10 months ago

        548 days with 53% cure and 3 biohazards. Thanks, Ashleign! :)

      • profile image

        Jake H 10 months ago

        Didn't have any of those gene helper things but 554 with 50%!!! thanks!

      • profile image

        Just Janet 10 months ago

        Brilliant! Worked on the first try. Finished in 606 days 55% cured.

      • profile image

        Britt Howard 10 months ago

        Wiped out humans in 570 days! 40 DNA points leftover after deadliest symptoms used. Cure only 55%!

      • profile image

        V1rus47 10 months ago

        590 days, 53% finished. Almost followed all the steps my disease keeps evolving. And thanks for the help

      • profile image

        Nekomaster 10 months ago

        got it on my first try with out the special genes. I probably just got lucky.

        Thanks for all your other tutorials, now I can move on to making a Bio-weapon :)

        ALso it might help if people put a few DNA points into symptoms that will help slow down the cure like paronioa and anemia to get the walking dead combo

      • profile image

        Ainzo 11 months ago

        561 days - 49% :) - thank you!!

      • profile image

        Chantel 11 months ago

        583 days and cure at 49% . Thank you so much for the walkthrough. Couldn't have done it without you!

      • profile image

        Pascal 11 months ago

        4 day -1000% cure

      • profile image

        James 11 months ago

        571 days 53% cure

      • profile image

        Level one 11 months ago

        622 days using guide, this was my second try.

      • profile image

        SeanK 11 months ago

        473 days, 41% cure

      • profile image

        lind 11 months ago

        635 days

      • profile image

        Seifer 12 months ago

        492 days, awesome tutorial

      • profile image

        Anonymous 12 months ago

        I did it in 534 days in Normal mode! This guide was extremely helpful

      • profile image

        Jace Bond 12 months ago

        I did it in 760 Days! Amazing! Didn’t follow exactly, but mostly! Thank you!

      • profile image

        Vitiate 12 months ago

        First go and did it in 537 days, great guide.

      • profile image

        Bexx 12 months ago

        600 Days :D

      • profile image

        Frances 12 months ago

        Five hundred twenty-seven days.

      • profile image

        Mike 12 months ago

        561 days

      • amyzzzzz123 profile image

        amyzzzzz123 12 months ago

        Beat it in 577 days :) thanks!

      • profile image

        orteam 12 months ago

        Worked :)

      • profile image

        MartianArcher 12 months ago

        First try and won. Excellent tutorial

      • profile image

        Shrim 12 months ago

        I got 684 days.

      • profile image

        Martint9179 12 months ago

        I messed up by going a bit too fast and skipping a step, so I had to devolve 2 symptoms. Even with the screw-up, I still killed off the world in 540 days with the cure at 51% on the first try. I didn't have any of the genes you listed at the top, so I used Aquacyte and Xerophile, but it still worked out really well. Thanks for uploading this strategy. Keep up the good work.

      • profile image

        autumn 12 months ago

        Started in Brazil, 587 days and cure was at 56%; but I didn't have genetic mimic, metabolic hijack, or extromophile.

      • profile image

        Cool 12 months ago

        573 days and 51 cure percent

      • profile image

        Harry 12 months ago

        Its work. 592 Days, 48% cure, I started it in China.

      • profile image

        David 13 months ago

        Worked in 685 days. I started in Greenland because others said it was hard to get it there. Otherwise I followed the directions exactly.

      • profile image

        Yeet 13 months ago

        lost, greenland never infected

      • profile image

        Amy 13 months ago

        I got the sterile ship problem right away and never spread to Greenland.

      • profile image

        Chriz 13 months ago

        797@ 67 cure was pretty interesting


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