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How to Beat "Pandemic 2" Strategy

The Search for an Answer

I searched all over the internet, and I could not find a suitable answer to this question. Therefore, I have played the game and fine-tuned all the different options to see what actually works and how to infect hard to reach places like Madagascar and New Zealand. I have put hours of research into this, so I hope it proves helpful.


"Pandemic 2" Plot

The plot of Pandemic 2 is described by it's creators as follows:

"Select your preferred life form to spread disease. Then infect everyone! Upgrade with delightful symptoms like vomiting, delirium and open sores. Yum, yum!"

They offer no strategies beyond that. There is a small tutorial that serves the purpose of leaving you feeling alone and abandoned in a world that needs to be overrun by disease.


Starting the Game Right

There are a few things that are rather obvious to do at the start.

  1. You want to keep visibility to a minimum. You can easily do this by not buying symptoms that increase it. Don't forget you can sell those that you already have to lower visibility.
  2. Avoid causing mass panic. You want to slowly spread around the world with only a fever or cough. This will prevent most ports and airports from closing. Once they close you are done for island nations like New Zealand and Madagascar.
  3. Use rodents and insects at the start to spread. This will take a long time but Air and water cause a lot of panic and will start a vaccination effort.
  4. Spread EVERYWHERE before you attempt to start killing people!
  5. I would recommend restarting until you get a start point in Madagascar as it seems nearly impossible to spread there!

"Pandemic 2" Symptoms Guide

Level 1

Sneezing, Buy 3 Sell 1

A sneeze is a sudden, forceful, involuntary burst of air through the nose and mouth.

Coughing, Buy 3 Sell 4

Coughing is an important way to keep your throat and airways clear. However, excessive coughing may mean you have an underlying disease or disorder.

Fever, Buy 5 Sell 3

Fever is the temporary increase in the body's temperature, in response to some disease or illness.

Sweating, Buy 2 Sell 3

Sweating is the release of a salty liquid from the body's sweat glands. This process is also called perspiration.

Vomiting, Buy 6 Sell 3

Scroll to Continue

Read More From Levelskip

Vomiting blood is a backward flowing (regurgitation) of blood through the upper gastrointestinal (GI) tract. The upper GI tract includes the stomach, mouth, throat, esophagus (the swallowing tube), and the first part of the small intestine.

Level 2

Fatigue, Buy 3 Sell 6

Fatigue is a feeling of weariness, tiredness, or lack of energy.

Diarrhea, Buy 8 Sell 4

Diarrhea is loose, watery, and frequent stool. Diarrhea is considered chronic (long-term) when you have had loose or frequent stools for more than 4 weeks.

Nausea, Buy 3 Sell 6

Nausea is the sensation of having an urge to vomit. Vomiting is forcing the contents of the stomach up through the esophagus and out of the mouth.

Pulmonary Edema, Buy 9 Sell 5

Pulmonary edema is an abnormal build up of fluid in the air sacs of the lungs, which leads to shortness of breath

Dementia, Buy 3 Sell 6

Dementia is a loss of brain function that occurs with certain diseases. It affects memory, thinking, language, judgment, and behavior.

Level 3

Hypersensitivity, Buy 7 Sell 3

Hypersensitivity pneumonitis is inflammation of the lungs due to breathing in a foreign substance, usually certain types of dust, fungus, or molds.

Ataxia, Buy 7 Sell 4

Ataxia is the sharp decline in motor skills. The cause of ataxia is often dysfunction in the cerebellum.

Kidney Failure, Buy 22 Sell 11

Depression, Buy 5 Sell 8

Hemorrhaging, Buy 22 Sell 12

Level 4, Buy 20

Liver Failure, Buy 20 Sell 10

Heartfailure, Buy 24 Sell 12

Blindness, Buy 4 Sell 10

Hypotonia, Buy 4 Sell 8

Encephalitis, Buy 21 Sell 12

Encephalitis is acute inflammation of the brain. Brain damage occurs as the brain pushes against the skull, and eventually results in death.

Natural Disasters Guide


Earthquakes greatly reduce the effectiveness of hospitals in the region.


Floods temporarily boost exposure to your disease if your disease is able to spread via water.


Hurricanes temporarily close airports due to high winds. Also temporarily closes schools and transit.


Droughts increase insect population, and boosts exposure to your disease if it is spreadable by insects.


Riots negate the effects of curfews.

The Best Guide to Beating "Pandemic 2" I Found Online!

I found this from Yahoo Answers.

"I went with parasite, and kept restarting the game in realistic mode until I had a couple of traits under my belt (durable is a personal fav, and pretty common) and my starting symptom was fever. I think I started in Cuba.

I sold my symptom, and bought drug resistance 1 & 2. Then I concentrated my DNA pts on moisture resistance and cold resistance. Once I got those to level 3, I started buying heat resistance.

All this time, I did not have anything for transmission. I waited until every country was infected (yep, even got Madagascar). In fact, Madagascar wasn't even the last to get infected! They kept their ports open for a while.

Once everyone was infected, I finished putting points on resistances, and started in on transmission. Around this time my disease became famous (ooooh) and they started working on a vaccine. Since most of the hospitals are shut down, and my drug resistance is maxed out, I have about 400+ days to hang out and infect people. I also *just* bought vomiting. There's lots of reasons to puke, and it makes the disease really contagious, so it's made the poor researchers' jobs just a little bit harder.

I'm still playing this particular game, but once I have my transmission vectors maxed I'm going to start buying the more lethal symptoms. Since the researchers are so flummoxed, I'm hoping to have enough time. Or that the vaccine will make my parasite resistant to any further attempts (had that happen on an earlier game).

Hope this helps!"

This seems to have worked! All the hospitals are shut down, so the vaccine development is on infinite. Everyone's infected and gonna die!

Some of these suggestions work, some don't. But this is the best guide I was able to find online.

Last Suggestions

Do not get discouraged. You can beat this game. It just takes some persistence.

You need to focus a lot on keeping visibility low, if not you will end up closing ports and airports that will not reopen—ever. Seems the world is so scared they close down for good, which I would say would be as good as being turned into the zombies everyone else is.

Keep symptoms very low, your goal is to infect every Country then start spreading it like wild fire. Play it down to a small cough or fever like the swine flu and you will beat Pandemic 2. If you all the sudden throw out a killer highly lethal cancer like disease then everyone will react right away and shut you down!

So, what have we learned? Use weaker symptoms until every country is infected. Then spread it faster, then make it lethal, keep it low visibility and use bacteria! Those are all the things you need to know to beat Pandemic II!

The Links Important to This Article


hannah on March 23, 2012:

i know its a cheat, but start as a bactedria and name it morethanacolditis and you start in, what i want to know is how do you start riots?

anonymusbillybob on March 15, 2012:

lol the first time i started madagascar was infected! :D lucky!

Good way another:

1. realistic, parasite

2.get everything for resistance

3. wait for it to spread around the world

4. buy heart problems and just wait...... :)=

anonymus on April 06, 2010:

Also a good way.

1. Do Realistic and Virus

2. Buy all tier 1 traits (this should help to very quickly infect your country and others).

3. Max out all resistance

4. Buy all transmission thingamijigs.

5. Slowly wait for more evolution points and unlock other tiers and symptoms.

6. End the world!!!!!!!!!!

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