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"Slay the Spire" Curse Cards Guide

Eric loves to write about video game-related topics. He has years of experience playing games and wants to share his thoughts.

In Slay the Spire, you collect and find many cards. But not all cards in the Slay the Spire are useful.

In this guide, I am going to explain what the curse cards in the game are and how you can deal with having them.

All the curse cards in Slay the Spire.

All the curse cards in Slay the Spire.

What Are Curse Cards?

Curse cards are a special type of card in Slay the Spire. When you have a curse card, they will be in your deck and show up in your hand during the turns you play.

Some curse cards don’t do anything other than take up space in your deck. But others have nasty negative effects that can hurt your chances of winning the game.

For a whole list of curse card effects, I recommend reading the Slay the Spire fandom page. This page is a very useful guide on curse cards. I used it as a resource to write this guide.

Why Curse Cards Are Annoying

One of the things I learned while playing Slay the Spire is that a smaller deck is better than a bigger one.

Ideally, you only want the cards you need so you can draw them more often.

Curse cards make this goal harder by taking up space. Even worse, some cards harm you the turn you draw them.

The doubt curse card gives you the weak stats effect at the end of your turn.

The doubt curse card gives you the weak stats effect at the end of your turn.

Can Curse Cards Ever Be Useful?

Two relics get stronger if you have curse cards.

  • The Darkstone Periapt increases your max health by six.
  • The Du-Vu doll increases your strength by one point for every curse card you currently have.

How Do You Get Curse Cards?

Here is how you can obtain curse cards.

Some Events Give Curses

Curses are sometimes given to you from interacting with events in the game. Some events will always give you a curse if you select a certain option.

You will often get a curse from an event if you do something evil. But some events give you curses when you would not expect them.

Some Relics Give Curses

The Calling Bell relic always gives the Curse of the Bell card. This card can’t be removed from your deck, and it is quite annoying.

If you have the cursed key relic, you will receive a new curse any time you open a chest.

Other Ways to Get Curse Cards

If you are playing on Ascension 10 or higher, you will start with the Ascender's Bane curse card. This card can’t be removed from your deck.

When you beat the game with a character, you unlock ascension levels. Every higher accession level makes the game harder in multiple ways.

You can get Pride curse cards when playing endless custom mode runs.

The Cursed key relic at the end of a boss fight.

The Cursed key relic at the end of a boss fight.

You Can Avoid Curse Cards

There is only one event in the game that gives you a curse card without you getting a chance to avoid it. It is the Wheel of Change event.

That smug gremlin doesn’t give you a chance to say no, and the wheel spin can give you a curse card.

But any other source of curse cards can be avoided. It is important to remember that you rarely have to get a curse card if you don’t want to.

Events only give you a curse as a punishment for doing something bad most of the time. So you can avoid getting cursed from events by just not doing those things.

You can avoid Ascender's Bane by just not playing Ascension 10 or higher.

Also, you don’t have to take the Calling Bell relic.

About the Omamori Relic

If you have the Omamori relic, the next two curses you would get are avoided.

With this relic, you can get away by taking curses in events because they can’t give them to you. Sorry pleading vagrant, but there is no shame in stealing from you now!

This event gives you a cursed card if you rummage choice.

This event gives you a cursed card if you rummage choice.

How to Remove Curse Cards

The easiest way to deal with curse cards is to remove them. There are multiple ways you can remove them.

But remember that some curse cards state that they can’t be removed.

You can’t remove Ascender's Bane, Curse of the Bell, or Necromicurse from your deck.

While at shops, you can pay to remove one card from your deck.

Remove Cards With Relics

Empty Cage allows you to remove any two cards from your deck. This relic is dropped after beating a boss.

Peace Pipe allows you to remove one card when you rest at campsites. You can remove curse cards.

You might think the Astrolabe would transform curse cards into safer cards. But the Astrolabe will transform curse cards into other curse cards.

Remove Cards With Events

Some events can remove a card. These events will allow you to remove curse cards.

The Ancient Writing event will allow you to remove one card from your deck.

At the Bonfire Spirits event, you can give them a curse card. The spirits will give you the Spirit Poop relic in return.

The relic does not do anything, and I think it is added to be a joke. It does remove one point from your final score if you win, though.

The Living Wall event will allow you to remove one card from your deck.

About the Parasite Curse Card

Be careful about removing the Parasite curse card! Removing this card will remove three max health points. It does not matter how you remove the card either.

This event removes all curse cards from your hand.

This event removes all curse cards from your hand.

You can pay gold at shops to remove a card from your hand.

You can pay gold at shops to remove a card from your hand.

When You Can’t Remove a Curse Card, Exhaust It

Sometimes you won’t be able to remove a curse card right away. Some curse cards can’t be removed at all.

But if you can exhaust the curse cards, you can temporally deal with them.

This method won’t remove the cards. So they will still show up in future fights. But at least for the current battle, you won’t have to deal with having them.

Once a card is exhausted, you will no longer draw it. Any effect the card would have at the end of the turn no longer happens as well.

You can exhaust almost every single curse card. This method will work on cards that can’t be removed from your deck.

But the Necromicurse is forever! When you exhaust this curse card, another copy is added to your deck. Once you get this curse, you have it for the rest of the run. You can’t avoid it.

Some cards give you the ability to exhaust other cards. If you want to review them all, I would check the Slay the Spire cards page on the Fandom wiki.

If you have the Blue Candle relic, you can exhaust curse cards at the cost of one health point. If you also have the Tungsten Rod relic, you won’t receive any damage.

There is a potion that lets you exhaust multiple cards from your hand.

I am using the Second Wind Inronclad card. It will remove the curse cards I have.

I am using the Second Wind Inronclad card. It will remove the curse cards I have.

Some Curse Cards Can Be Mitigated by Discarding Them Form Your Hand

Sometimes you might not be able to remove or exhaust cards.

But there is one last trick you can use on some curse cards. You can remove them from your hand. By discarding a curse card from your hand, you avoid any effects that will happen.

There are multiple ways to remove cards from your current hand. Certain cards and relics allow you to remove cards from your current hand.

This method is even more temporary than exhausting cards.

You will still will be able to draw the card on future turns, but some fights only last a few turns, so this method can be quite helpful.

This method only helps on cards that do something when the turn ends or while the card is in your hand.

Removing cards that don’t do anything from your hand won’t help you since they are still in your deck.

I can pick a curse card to discard.

I can pick a curse card to discard.

I can discard the curse cards in my hand.

I can discard the curse cards in my hand.

© 2021 Eric Farmer

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